Clinical Characteristics of 118 Patients With DLCL Who Had DNA That Was Analyzable for t(14; 18) by PCR (bcl-2 gene rearrangement)
| Characteristic . | No. t(14; 18) Positive (%) . | No. t(14; 18) Negative (%) . | P . |
|---|---|---|---|
| Total | 14 (100) | 104 (100) | — |
| Age >60 yr | 0 | 34 (33) | .03 |
| Stage III or IV | 7 (50) | 66 (63) | NS |
| Elevated LDH | 10 (71) | 76 (73) | NS |
| Performance status (ECOG) 2-4 | 3 (21) | 17 (16) | NS |
| Extranodal sites >1 | 3 (21) | 31 (30) | NS |
| BM involvement | 0 | 10 (10) | NS |
| CR rate | 12 (86) | 88 (85) | NS |
| Characteristic . | No. t(14; 18) Positive (%) . | No. t(14; 18) Negative (%) . | P . |
|---|---|---|---|
| Total | 14 (100) | 104 (100) | — |
| Age >60 yr | 0 | 34 (33) | .03 |
| Stage III or IV | 7 (50) | 66 (63) | NS |
| Elevated LDH | 10 (71) | 76 (73) | NS |
| Performance status (ECOG) 2-4 | 3 (21) | 17 (16) | NS |
| Extranodal sites >1 | 3 (21) | 31 (30) | NS |
| BM involvement | 0 | 10 (10) | NS |
| CR rate | 12 (86) | 88 (85) | NS |
Abbreviation: NS, not significant.