Ig/c-myc Junction Sequences From Control and Indomethacin Treated Mice
Day . | Mouse No. . | Treatment . | Mesenteric Fragment4-150 . | Ig Sα (chr 12)‡ . | Junction4-151 . | c-myc (chr 15)‡ (5′-3′) . |
---|---|---|---|---|---|---|
. | . | . | . | (3′-5′) MUSIALPHA . | . | From Exon 1 Pos. 1 . |
30 | 20 | Alc | S6, S10 | 5,108 | A | 527 |
5,108 | T | 526 | ||||
30 | 8 | Alc | S29 | 4,080 | 247 | |
30 | 11 | Alc | S33, S34, S35 | 5,636 | gagac | 475 |
30 | 16 | Alc | S39A | 3,693 | 689 | |
30 | 4 | Indo | T34 | 3,681 | TC | 414 |
30 | 17 | Indo | S1, S3 | 2,433 | 600 | |
30 | 14 | Indo | T5A, T5B | 499 (Sμ) MUSIGCD09‡ | G | 967 |
30 | 1 | Indo | T13 | 2,919 | 973 | |
30 | 9 | Indo | T19 | 824 (Sμ) MUSIGHMY‡ | 837 | |
82 | 9ρ | H2O | X32 | 5,148 | G | 1,039 |
X33A | 46 (Sμ) MUSIGCD09‡ | 521 | ||||
82 | 28 | Alc | X48 | 4,409 | AA | 922 |
87 | 21 | Alc | Y13 | 5,432 | A | 1,392 |
89 | 13 | Alc | Z29A, Z29B | 4,385 | ag | 567 |
4,382 | G | 567 | ||||
89 | 16 | Alc | Z26B, Z29 | 5,426 | CCTAG | 114 |
87 | 30ρ | Indo | Z32 | 4,090 | C | 422 |
Z34 | 4,460 | ga | 680 | |||
87 | 25 | Indo | Y9 | 3,521 | T | 508 |
89 | 27 | Indo | Y19 | 3,954 | 977 | |
89 | 15ρ | Indo | Z16 | 4,172 | T | 1,054 |
Z19 | 3,570 | 1,013 | ||||
89 | 11 | Indo | Z43, Z43A | 4,243 | CG | 799 |
Day . | Mouse No. . | Treatment . | Mesenteric Fragment4-150 . | Ig Sα (chr 12)‡ . | Junction4-151 . | c-myc (chr 15)‡ (5′-3′) . |
---|---|---|---|---|---|---|
. | . | . | . | (3′-5′) MUSIALPHA . | . | From Exon 1 Pos. 1 . |
30 | 20 | Alc | S6, S10 | 5,108 | A | 527 |
5,108 | T | 526 | ||||
30 | 8 | Alc | S29 | 4,080 | 247 | |
30 | 11 | Alc | S33, S34, S35 | 5,636 | gagac | 475 |
30 | 16 | Alc | S39A | 3,693 | 689 | |
30 | 4 | Indo | T34 | 3,681 | TC | 414 |
30 | 17 | Indo | S1, S3 | 2,433 | 600 | |
30 | 14 | Indo | T5A, T5B | 499 (Sμ) MUSIGCD09‡ | G | 967 |
30 | 1 | Indo | T13 | 2,919 | 973 | |
30 | 9 | Indo | T19 | 824 (Sμ) MUSIGHMY‡ | 837 | |
82 | 9ρ | H2O | X32 | 5,148 | G | 1,039 |
X33A | 46 (Sμ) MUSIGCD09‡ | 521 | ||||
82 | 28 | Alc | X48 | 4,409 | AA | 922 |
87 | 21 | Alc | Y13 | 5,432 | A | 1,392 |
89 | 13 | Alc | Z29A, Z29B | 4,385 | ag | 567 |
4,382 | G | 567 | ||||
89 | 16 | Alc | Z26B, Z29 | 5,426 | CCTAG | 114 |
87 | 30ρ | Indo | Z32 | 4,090 | C | 422 |
Z34 | 4,460 | ga | 680 | |||
87 | 25 | Indo | Y9 | 3,521 | T | 508 |
89 | 27 | Indo | Y19 | 3,954 | 977 | |
89 | 15ρ | Indo | Z16 | 4,172 | T | 1,054 |
Z19 | 3,570 | 1,013 | ||||
89 | 11 | Indo | Z43, Z43A | 4,243 | CG | 799 |
Fragments on the same line contain similar junctions isolated from different sectors. For each mouse there were 5 mesenteric fragments: the letter = randomized series, the numeral = the fragment. Thus in mouse #20, 2 separate fragments were isolated (S6, S10) that had the same junction sequence (except for overlaps which do not reflect significant differences).
The Ig and myc sequences at the junction shared common bases are capitalized while contained inserts are lower case.
Reference sequences from Genbank.
ρ Two different junction sequences were identified from these mice.