Table 4.

Ig/c-myc Junction Sequences From Control and Indomethacin Treated Mice

DayMouse No.TreatmentMesenteric Fragment4-150Ig Sα (chr 12)Junction4-151c-myc (chr 15) (5′-3′)
(3′-5′) MUSIALPHAFrom Exon 1 Pos. 1
30 20 Alc S6, S10 5,108 527 
    5,108 526 
30 Alc S29 4,080  247 
30 11 Alc S33, S34, S35 5,636 gagac 475 
30 16 Alc S39A 3,693  689 
30 Indo T34 3,681 TC 414 
30 17 Indo S1, S3 2,433  600 
30 14 Indo T5A, T5B 499 (Sμ) MUSIGCD09 967 
30 Indo T13 2,919  973 
30 Indo T19 824 (Sμ) MUSIGHMY  837 
82 9ρ H2X32 5,148 1,039 
   X33A 46 (Sμ) MUSIGCD09  521 
82 28 Alc X48 4,409 AA 922 
87 21 Alc Y13 5,432 1,392 
89 13 Alc Z29A, Z29B 4,385 ag 567 
    4,382 567 
89 16 Alc Z26B, Z29 5,426 CCTAG 114 
87 30ρ Indo Z32 4,090 422 
   Z34 4,460 ga 680 
87 25 Indo Y9 3,521 508 
89 27 Indo Y19 3,954  977 
89 15ρ Indo Z16 4,172 1,054 
   Z19 3,570  1,013 
89 11 Indo Z43, Z43A 4,243 CG 799 
DayMouse No.TreatmentMesenteric Fragment4-150Ig Sα (chr 12)Junction4-151c-myc (chr 15) (5′-3′)
(3′-5′) MUSIALPHAFrom Exon 1 Pos. 1
30 20 Alc S6, S10 5,108 527 
    5,108 526 
30 Alc S29 4,080  247 
30 11 Alc S33, S34, S35 5,636 gagac 475 
30 16 Alc S39A 3,693  689 
30 Indo T34 3,681 TC 414 
30 17 Indo S1, S3 2,433  600 
30 14 Indo T5A, T5B 499 (Sμ) MUSIGCD09 967 
30 Indo T13 2,919  973 
30 Indo T19 824 (Sμ) MUSIGHMY  837 
82 9ρ H2X32 5,148 1,039 
   X33A 46 (Sμ) MUSIGCD09  521 
82 28 Alc X48 4,409 AA 922 
87 21 Alc Y13 5,432 1,392 
89 13 Alc Z29A, Z29B 4,385 ag 567 
    4,382 567 
89 16 Alc Z26B, Z29 5,426 CCTAG 114 
87 30ρ Indo Z32 4,090 422 
   Z34 4,460 ga 680 
87 25 Indo Y9 3,521 508 
89 27 Indo Y19 3,954  977 
89 15ρ Indo Z16 4,172 1,054 
   Z19 3,570  1,013 
89 11 Indo Z43, Z43A 4,243 CG 799 
F4-150

Fragments on the same line contain similar junctions isolated from different sectors. For each mouse there were 5 mesenteric fragments: the letter = randomized series, the numeral = the fragment. Thus in mouse #20, 2 separate fragments were isolated (S6, S10) that had the same junction sequence (except for overlaps which do not reflect significant differences).

F4-151

The Ig and myc sequences at the junction shared common bases are capitalized while contained inserts are lower case.

Reference sequences from Genbank.

ρ Two different junction sequences were identified from these mice.

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