Statistical Analysis of Brain Engraftment Parameters in Newborn Mice
Effect
.
F (df)
.
P
.
Blood engraftment
136.0 (1)
.0001
Blood engraftment × genotype
23.9 (1)
.0001
Effect
.
F (df)
.
P
.
Blood engraftment
136.0 (1)
.0001
Blood engraftment × genotype
23.9 (1)
.0001
The number of donor-derived cells in the brains of newborn mice 3 months post-BMT was modeled to evaluate the effects of blood engraftment, genotype, and their interactions [Model F(3,39) = 23.9; P = .0001]. The number of donor-derived cells in the brain correlates with the number in blood (see Fig 5) and is significantly higher in ASMKO as compared with normal mice.