Peripheral Blood Analysis of Engrafted LGL-SCID Mice
| Total and Differential WBC Counts in Tumor-Injected and Mock-Injected SCID Mice . | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mouse ID . | WBC . | RBC . | % of Nucleated Cells . | Hb . | R% . | ||||
| . | . | . | L . | N . | M . | E . | LGL . | . | . |
| F8 LGL cell line-injected | |||||||||
| SC-1 | 10.5 | 4.85 | 11 | 58 | 1 | 0 | 30 | 7.5 | 18.2 |
| SC-2 | 10.7 | 4.80 | 5 | 72 | 2 | 0 | 21 | 7.3 | 9.8 |
| SC-3 | 9.7 | 4.63 | 5 | 71 | 2 | 0 | 22 | 7.2 | 12.7 |
| SC-4 | 13.5 | 6.63 | 8 | 70 | 2 | 0 | 20 | 9.0 | 2.4 |
| Average | 11.1* | 5.22* | 7* | 68† | 2 | 0 | 23* | 7.8* | 10.8‡Mock-injected |
| NML-1 | 2.0 | 10.22 | 59 | 40 | 1 | 0 | 0 | 14.8 | 0.7 |
| NML-2 | 1.8 | 8.94 | 53 | 45 | 2 | 0 | 0 | 13.3 | 2.9 |
| NML-3 | 1.6 | 8.62 | 49 | 48 | 3 | 0 | 0 | 12.9 | 1.3 |
| NML-4 | 4.5 | 9.44 | 40 | 58 | 2 | 0 | 0 | 13.7 | 0.8 |
| NML-5 | 3.7 | 9.21 | 42 | 54 | 4 | 0 | 0 | 13.8 | 2.0 |
| Average | 2.7 | 9.29 | 49 | 49 | 2 | 0 | 0 | 13.7 | 1.5 |
| Total and Differential WBC Counts in Tumor-Injected and Mock-Injected SCID Mice . | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mouse ID . | WBC . | RBC . | % of Nucleated Cells . | Hb . | R% . | ||||
| . | . | . | L . | N . | M . | E . | LGL . | . | . |
| F8 LGL cell line-injected | |||||||||
| SC-1 | 10.5 | 4.85 | 11 | 58 | 1 | 0 | 30 | 7.5 | 18.2 |
| SC-2 | 10.7 | 4.80 | 5 | 72 | 2 | 0 | 21 | 7.3 | 9.8 |
| SC-3 | 9.7 | 4.63 | 5 | 71 | 2 | 0 | 22 | 7.2 | 12.7 |
| SC-4 | 13.5 | 6.63 | 8 | 70 | 2 | 0 | 20 | 9.0 | 2.4 |
| Average | 11.1* | 5.22* | 7* | 68† | 2 | 0 | 23* | 7.8* | 10.8‡Mock-injected |
| NML-1 | 2.0 | 10.22 | 59 | 40 | 1 | 0 | 0 | 14.8 | 0.7 |
| NML-2 | 1.8 | 8.94 | 53 | 45 | 2 | 0 | 0 | 13.3 | 2.9 |
| NML-3 | 1.6 | 8.62 | 49 | 48 | 3 | 0 | 0 | 12.9 | 1.3 |
| NML-4 | 4.5 | 9.44 | 40 | 58 | 2 | 0 | 0 | 13.7 | 0.8 |
| NML-5 | 3.7 | 9.21 | 42 | 54 | 4 | 0 | 0 | 13.8 | 2.0 |
| Average | 2.7 | 9.29 | 49 | 49 | 2 | 0 | 0 | 13.7 | 1.5 |
Abbreviations: Total WBC count is expressed as number (×10−12) per liter; Hb, hemoglobin expressed as g/dL; L, lymphocytes; N, neutrophils; M, monocytes; E, eosinophils; R, reticulocytes; LGL, large granular lymphocytes; RBC, red blood cells.
Significantly different from mock-injected SCID mice (P < .001).
Significantly different from mock-injected SCID mice (P < .01).
Significantly different from mock-injected SCID mice (P < .05).