Table 1. Expression of Wild-Type and... | American Society of Hematology

Table 1.

Expression of Wild-Type and Mutated p53 as Well as p21 and p27 in MM Cell Lines and MM Cells of Patients

Cells	Wt p53^*	Mt p53^†	p21^‡	p27^‡
OCI-My5	+	+	+	++
RPMI-8226	−	+++	+	++
U-266	−	+++	+	+
HSS	−	+++	+	+++
S6B45	+	+	++	+++
ARH-77	+	+++	−	−
JKB	+	−	++	+
Patient no. 1	+	+	+	++
Patient no. 2	−	+	+	++
Patient no. 3	+	−	+	+
Patient no. 4	+	−	+	++
Patient no. 5	+	−	+	++

Cells	Wt p53^*	Mt p53^†	p21^‡	p27^‡
OCI-My5	+	+	+	++
RPMI-8226	−	+++	+	++
U-266	−	+++	+	+
HSS	−	+++	+	+++
S6B45	+	+	++	+++
ARH-77	+	+++	−	−
JKB	+	−	++	+
Patient no. 1	+	+	+	++
Patient no. 2	−	+	+	++
Patient no. 3	+	−	+	+
Patient no. 4	+	−	+	++
Patient no. 5	+	−	+	++

Protein expression levels were compared in the same number of cells (−, undetectable; +, weakly expressed; ++, moderately expressed; +++, highly expressed).

Cells were irradiated at 3 Gy.

†

Expression was not altered by irradiation.

‡

Cells were not irradiated.

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