Expression of Ig Isotypes by Tumor Cells Assessed by Immunohistochemistry in Frozen Biopsy Specimens
| Biopsy . | Histology . | Ki-67* . | Light Chain* . | IgM* . | IgD* . | IgG* . | IgA* . |
|---|---|---|---|---|---|---|---|
| BA-1F | FCL | 20 | 100 λ | Single cells† | − | >80 | 100 |
| EJ-1F | DLCL | 60 | 100 κ | 100 | 20 | 30 | − |
| EJ-2F | 60 | 100 κ | 100 | 20 | − | − | |
| EJ-3F | 60 | − | 100 | − | − | − | |
| BR-2F | DLCL | 60 | 100 κ | 100 | − | 90 | − |
| Biopsy . | Histology . | Ki-67* . | Light Chain* . | IgM* . | IgD* . | IgG* . | IgA* . |
|---|---|---|---|---|---|---|---|
| BA-1F | FCL | 20 | 100 λ | Single cells† | − | >80 | 100 |
| EJ-1F | DLCL | 60 | 100 κ | 100 | 20 | 30 | − |
| EJ-2F | 60 | 100 κ | 100 | 20 | − | − | |
| EJ-3F | 60 | − | 100 | − | − | − | |
| BR-2F | DLCL | 60 | 100 κ | 100 | − | 90 | − |
Abbreviation: −, negative.
Percent positive tumor cells.
Morphologically single IgM-bearing cells were localized within and without the neoplastic follicles; however, because no confluent groups of cells were positive, it was not possible definitely to attribute IgM+ cells to the tumor cell population.