PCR Results, Treatments, and Clinical Outcome of the 15 APL Patients
| Pt. No. . | Age/Sex . | PML/RARα Junction Type . | Initial Therapy/Consolid. . | CR1 Length (mo) . | Therapy of Relapse/Consolid. . | Time to ABMT (mo from CR2) . | Pre-ABMT PCR* . | CR2 Length (mo post-ABMT) . | Outcome . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 50/F | bcr3 | IDA/yes | 12 | ATRA/no | 2 | Positive | 2 | Relapsed/dead |
| 2 | 38/M | bcr1 | DNR/yes | 16 | ATRA/no | 2 | Positive | 5 | Relapsed/dead |
| 3 | 17/F | bcr3 | IDA/yes | 10 | ATRA/no | 2 | Positive | 7 | Relapsed/dead |
| 4 | 43/M | bcr1 | IDA + AraC/ATRA/yes | 20 | ATRA/yes | 2 | Positive | 3 | Relapsed/dead |
| 5 | 40/M | bcr2 | IDA/yes | 40 | ATRA/yes | 3 | Positive | 9 | Relapsed/dead |
| 6 | 39/F | bcr1 | IDA/yes | 6 | ATRA/yes | 6 | Positive | 4 | Relapsed/dead |
| 7 | 10/M | bcr3 | LAM 8704 | 6 | ATRA/yes | 7 | Positive | 7 | Relapsed/dead |
| 8 | 46/F | bcr1 | IDA + AraC/yes | 18 | ATRA/yes | 2 | Negative | 60+ | A & W† |
| 9 | 23/F | bcr3 | IDA + AraC/yes | 12 | ATRA/yes | 2 | Negative | 44+ | A & W |
| 10 | 27/M | bcr1 | IDA/yes | 12 | ATRA/yes | 2 | Negative | 27+ | A & W |
| 11 | 45/F | bcr1 | IDA + AraC/yes | 22 | ATRA/yes | 3 | Negative | 10 | Relapsed/dead |
| 12 | 31/M | bcr1 | IDA + AraC/yes | 13 | ATRA/Mitox + AraC/yes | 4 | Negative | 36 | Dead‡ |
| 13 | 35/F | bcr3 | AIDA/yes | 13 | ATRA/yes | 2 | Negative | 15+ | A & W |
| 14 | 53/F | bcr1 | AIDA/yes | 11 | ATRA/yes | 3 | Negative | 20+ | A & W |
| 15 | 32/M | bcr1 | IDA + AraC/yes | 11 | ATRA/yes | 5 | Negative | 30+ | A & W |
| Pt. No. . | Age/Sex . | PML/RARα Junction Type . | Initial Therapy/Consolid. . | CR1 Length (mo) . | Therapy of Relapse/Consolid. . | Time to ABMT (mo from CR2) . | Pre-ABMT PCR* . | CR2 Length (mo post-ABMT) . | Outcome . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 50/F | bcr3 | IDA/yes | 12 | ATRA/no | 2 | Positive | 2 | Relapsed/dead |
| 2 | 38/M | bcr1 | DNR/yes | 16 | ATRA/no | 2 | Positive | 5 | Relapsed/dead |
| 3 | 17/F | bcr3 | IDA/yes | 10 | ATRA/no | 2 | Positive | 7 | Relapsed/dead |
| 4 | 43/M | bcr1 | IDA + AraC/ATRA/yes | 20 | ATRA/yes | 2 | Positive | 3 | Relapsed/dead |
| 5 | 40/M | bcr2 | IDA/yes | 40 | ATRA/yes | 3 | Positive | 9 | Relapsed/dead |
| 6 | 39/F | bcr1 | IDA/yes | 6 | ATRA/yes | 6 | Positive | 4 | Relapsed/dead |
| 7 | 10/M | bcr3 | LAM 8704 | 6 | ATRA/yes | 7 | Positive | 7 | Relapsed/dead |
| 8 | 46/F | bcr1 | IDA + AraC/yes | 18 | ATRA/yes | 2 | Negative | 60+ | A & W† |
| 9 | 23/F | bcr3 | IDA + AraC/yes | 12 | ATRA/yes | 2 | Negative | 44+ | A & W |
| 10 | 27/M | bcr1 | IDA/yes | 12 | ATRA/yes | 2 | Negative | 27+ | A & W |
| 11 | 45/F | bcr1 | IDA + AraC/yes | 22 | ATRA/yes | 3 | Negative | 10 | Relapsed/dead |
| 12 | 31/M | bcr1 | IDA + AraC/yes | 13 | ATRA/Mitox + AraC/yes | 4 | Negative | 36 | Dead‡ |
| 13 | 35/F | bcr3 | AIDA/yes | 13 | ATRA/yes | 2 | Negative | 15+ | A & W |
| 14 | 53/F | bcr1 | AIDA/yes | 11 | ATRA/yes | 3 | Negative | 20+ | A & W |
| 15 | 32/M | bcr1 | IDA + AraC/yes | 11 | ATRA/yes | 5 | Negative | 30+ | A & W |