Table 3. TCRBV Repertoire During IFN-α... | American Society of Hematology

Table 3.

TCRBV Repertoire During IFN-α Therapy Calculated as Absolute Numbers TCRBV⁺ Cells per Microliter of Blood

Day IFN-α	Patient A		Patient G		Controls (n = 5)
Day IFN-α	0	+1,183	+7	+463	Mean	Range
CD3	2,509	836	6,042	4,754	1,206	688-1,955
TCRBV
2	141	55	733^*	414	83	47-135
3	617	63	36	43	40	0-84
5.1	80	33	36	52	63	36-102
5.2/3	50	21	42	38	34	16-58
6.1	6	1	30	10	17	0-36
6.7	70	28	211	81	39	0-79
7.1	25	16	18	29	14	8-23
8.1/2	90	28	218	133	52	30-84
9.1	103	28	24	29	35	20-57
11.1/2	13	3	12	14	7	3-13
12.2	38	11	30	19	18	10-29
13.1/2	55	34	296	300	64	36-104
13.6	13	11	24	14	19	11-31
14	73	33	18	57	47	0-94
16	20	7	24	14	13	6-24
17	251	48	284	48	65	18-112
18	171	9	48	10	14	0-35
20	35	20	436	252	30	0-66
21.3	48	15	79	86	31	18-51
22	28	20	199	176	43	25-70
23	25	8	6	10	10	6-16

Day IFN-α	Patient A		Patient G		Controls (n = 5)
Day IFN-α	0	+1,183	+7	+463	Mean	Range
CD3	2,509	836	6,042	4,754	1,206	688-1,955
TCRBV
2	141	55	733^*	414	83	47-135
3	617	63	36	43	40	0-84
5.1	80	33	36	52	63	36-102
5.2/3	50	21	42	38	34	16-58
6.1	6	1	30	10	17	0-36
6.7	70	28	211	81	39	0-79
7.1	25	16	18	29	14	8-23
8.1/2	90	28	218	133	52	30-84
9.1	103	28	24	29	35	20-57
11.1/2	13	3	12	14	7	3-13
12.2	38	11	30	19	18	10-29
13.1/2	55	34	296	300	64	36-104
13.6	13	11	24	14	19	11-31
14	73	33	18	57	47	0-94
16	20	7	24	14	13	6-24
17	251	48	284	48	65	18-112
18	171	9	48	10	14	0-35
20	35	20	436	252	30	0-66
21.3	48	15	79	86	31	18-51
22	28	20	199	176	43	25-70
23	25	8	6	10	10	6-16

*Values exceeding the mean ± 3 × SD of normal controls are given in boldface type.