PB Cell Levels in hGMR Tg-Mice Injected With hGM-CSF
| PB Analysis . | Injected With hGM-CSF . | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Normal Mice . | Tg-Mice . | . | . | . | . | . | |||||
| . | 0 ng . | 500 ng . | 0 ng . | 20 ng . | 100 ng . | 500 ng . | 2500 ng . | . | . | . | . | . |
| WBC, no. × 103/μL | 3.7 ± 0.8 | 4.0 ± 0.7 | 3.4 ± 0.6 | 3.9 ± 2.6 | 5.3 ± 0.2 | 24.5 ± 8.6 | 64.5 ± 28.8 | |||||
| Differential count (%) | ||||||||||||
| Neutrophils (stab) | 0.5 ± 0.5 | 1.8 ± 1.2 | 1.5 ± 0.6 | 2.0 ± 0.7 | 1.8 ± 1.0 | 1.0 ± 1.1 | 0.3 ± 0.3 | |||||
| (seg) | 34.7 ± 4.1 | 36.7 ± 4.5 | 31.1 ± 4.6 | 36.5 ± 0.7 | 27.3 ± 5.8 | 13.7 ± 8.2 | 14.8 ± 3.3 | |||||
| Lymphocytes | 64.0 ± 4.4 | 60.0 ± 5.6 | 65.8 ± 4.3 | 60.0 ± 2.1 | 69.0 ± 6.1 | 86.1 ± 4.7 | 82.8 ± 4.1 | |||||
| Eosinophils | 0 ± 0 | 0.8 ± 0.3 | 0.5 ± 0.4 | 0.5 ± 0.7 | 0.3 ± 0.3 | 0.8 ± 0.6 | 0.7 ± 0.3 | |||||
| Monocytes | 0.8 ± 0.6 | 0.7 ± 0.3 | 1.1 ± 0.6 | 1.0 ± 0 | 1.5 ± 0.9 | 1.6 ± 0.8 | 1.3 ± 0.6 | |||||
| RBC, no. × 103/μL | 86.0 ± 1.9 | 83.3 ± 3.5 | 86.3 ± 3.4 | 86.5 ± 2.5 | 89.2 ± 0.5 | 88.0 ± 5.6 | 82.8 ± 4.3 | |||||
| Hematocrit (%) | 45.6 ± 0.4 | 43.0 ± 2.3 | 45.0 ± 1.9 | 45.2 ± 1.1 | 47.5 ± 0.1 | 49.0 ± 3.1 | 47.1 ± 2.3 | |||||
| Hb (g/dL) | 14.9 ± 0.2 | 13.8 ± 0.8 | 14.4 ± 0.6 | 14.3 ± 0.5 | 14.8 ± 0.1 | 14.6 ± 0.8 | 13.6 ± 0.5 | |||||
| Reticulocytes, % of total RBC | 2.2 ± 0.5 | 1.9 ± 0.7 | 2.5 ± 1.0 | 3.4 ± 0.8 | 4.2 ± 0.8 | 8.6 ± 2.7 | 6.3 ± 1.6 | |||||
| Platelets, no. × 103/μL | 918.0 ± 68.6 | 988.7 ± 51.0 | 997.2 ± 121.9 | 1028.0 ± 113.1 | 920.0 ± 25.4 | 433.6 ± 128.8 | 551.7 ± 47.0 | |||||
| PB Analysis . | Injected With hGM-CSF . | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Normal Mice . | Tg-Mice . | . | . | . | . | . | |||||
| . | 0 ng . | 500 ng . | 0 ng . | 20 ng . | 100 ng . | 500 ng . | 2500 ng . | . | . | . | . | . |
| WBC, no. × 103/μL | 3.7 ± 0.8 | 4.0 ± 0.7 | 3.4 ± 0.6 | 3.9 ± 2.6 | 5.3 ± 0.2 | 24.5 ± 8.6 | 64.5 ± 28.8 | |||||
| Differential count (%) | ||||||||||||
| Neutrophils (stab) | 0.5 ± 0.5 | 1.8 ± 1.2 | 1.5 ± 0.6 | 2.0 ± 0.7 | 1.8 ± 1.0 | 1.0 ± 1.1 | 0.3 ± 0.3 | |||||
| (seg) | 34.7 ± 4.1 | 36.7 ± 4.5 | 31.1 ± 4.6 | 36.5 ± 0.7 | 27.3 ± 5.8 | 13.7 ± 8.2 | 14.8 ± 3.3 | |||||
| Lymphocytes | 64.0 ± 4.4 | 60.0 ± 5.6 | 65.8 ± 4.3 | 60.0 ± 2.1 | 69.0 ± 6.1 | 86.1 ± 4.7 | 82.8 ± 4.1 | |||||
| Eosinophils | 0 ± 0 | 0.8 ± 0.3 | 0.5 ± 0.4 | 0.5 ± 0.7 | 0.3 ± 0.3 | 0.8 ± 0.6 | 0.7 ± 0.3 | |||||
| Monocytes | 0.8 ± 0.6 | 0.7 ± 0.3 | 1.1 ± 0.6 | 1.0 ± 0 | 1.5 ± 0.9 | 1.6 ± 0.8 | 1.3 ± 0.6 | |||||
| RBC, no. × 103/μL | 86.0 ± 1.9 | 83.3 ± 3.5 | 86.3 ± 3.4 | 86.5 ± 2.5 | 89.2 ± 0.5 | 88.0 ± 5.6 | 82.8 ± 4.3 | |||||
| Hematocrit (%) | 45.6 ± 0.4 | 43.0 ± 2.3 | 45.0 ± 1.9 | 45.2 ± 1.1 | 47.5 ± 0.1 | 49.0 ± 3.1 | 47.1 ± 2.3 | |||||
| Hb (g/dL) | 14.9 ± 0.2 | 13.8 ± 0.8 | 14.4 ± 0.6 | 14.3 ± 0.5 | 14.8 ± 0.1 | 14.6 ± 0.8 | 13.6 ± 0.5 | |||||
| Reticulocytes, % of total RBC | 2.2 ± 0.5 | 1.9 ± 0.7 | 2.5 ± 1.0 | 3.4 ± 0.8 | 4.2 ± 0.8 | 8.6 ± 2.7 | 6.3 ± 1.6 | |||||
| Platelets, no. × 103/μL | 918.0 ± 68.6 | 988.7 ± 51.0 | 997.2 ± 121.9 | 1028.0 ± 113.1 | 920.0 ± 25.4 | 433.6 ± 128.8 | 551.7 ± 47.0 | |||||