Table 1.

Whole Blood TF PCA and FVIIa Data From Figs 2 and 4 

GroupSamples (n) TF PCA (U/mL) (GM [CI95])Samples (n) [FVIIa] (ng/mL) (GM [CI95])
Controls  65  11.2 (8.9-14.0)  55 1.77 (1.47-2.14)  
 Caucasian  54  12.2 (9.6-14.0) 
 Black  11  7.2 (4.2-12.5)  
SCD  85 41.8 (33.4-52.2)-150 34  0.77 (0.64-0.93)-151 
 ≤16 yr old 44  44.6 (33.0-60.4)-150 13  0.89 (0.69-1.15)-151 
 >16 yr old  41  35.0 (25.2-48.5)-150 21 0.70 (0.55-0.90)-150 
 Crisis  42  35.3 (25.0-49.9)-151 15  0.95 (0.77-1.18)-151 
 Noncrisis  43 49.9 (37.2-65.0)-150 19  0.65 (0.50-0.85)-150 
 HbSC  15 33.8 (19.2-59.5)-152 7  0.95 (0.73-1.23)-152 
 HbSS 70  45.2 (35.6-57.4)-150 27  0.73 (0.58-0.91)-150 
GroupSamples (n) TF PCA (U/mL) (GM [CI95])Samples (n) [FVIIa] (ng/mL) (GM [CI95])
Controls  65  11.2 (8.9-14.0)  55 1.77 (1.47-2.14)  
 Caucasian  54  12.2 (9.6-14.0) 
 Black  11  7.2 (4.2-12.5)  
SCD  85 41.8 (33.4-52.2)-150 34  0.77 (0.64-0.93)-151 
 ≤16 yr old 44  44.6 (33.0-60.4)-150 13  0.89 (0.69-1.15)-151 
 >16 yr old  41  35.0 (25.2-48.5)-150 21 0.70 (0.55-0.90)-150 
 Crisis  42  35.3 (25.0-49.9)-151 15  0.95 (0.77-1.18)-151 
 Noncrisis  43 49.9 (37.2-65.0)-150 19  0.65 (0.50-0.85)-150 
 HbSC  15 33.8 (19.2-59.5)-152 7  0.95 (0.73-1.23)-152 
 HbSS 70  45.2 (35.6-57.4)-150 27  0.73 (0.58-0.91)-150 

Values are presented as geometric means (GM) and 95% confidence intervals (CI95). P values (all v pooled controls) are as shown by the symbols. For WBTF PCA, P = NS for Caucasian versus Black controls, SCD ≤16 years versus >16 years, HbSC versus HbSS disease, and SCD crisis versus noncrisis. For plasma [FVIIa], P < .05 for crisis versus noncrisis; P = NS for SCD ≤16 years versus >16 years, and for HbSC versus HbSS disease.

F0-150

P < .000001.

F0-151

P < .0005.

F0-152

P < .005.

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