Effect of PF4 and p34-58 onCFU-MK Growth in the Presence or Absence of Heparin
| . | 0 U/mL Heparin . | 5 U/mL Heparin . |
|---|---|---|
| Control | 100 ± 6.6 | 112 ± 6.6 |
| PF4 | 66.7 ± 2.1* | 99.2 ± 2.9 |
| p34-58 | 65.8 ± 3.7* | 67.9 ± 7.1* |
| . | 0 U/mL Heparin . | 5 U/mL Heparin . |
|---|---|---|
| Control | 100 ± 6.6 | 112 ± 6.6 |
| PF4 | 66.7 ± 2.1* | 99.2 ± 2.9 |
| p34-58 | 65.8 ± 3.7* | 67.9 ± 7.1* |
Values are expressed as the mean ± SEM of triplicate determination obtained from three separate experiments. One hundred percent (100%) corresponds to the control value (PBS) (45 CFU-MK/mL). Formation of CFU-MK from PF4 (630 nmol/L) or p34-58 (22 nmol/L) treated bone marrow cells. Heparin was added after plasma-clot formation.
P < .01 as compared with control value determined by the Student's t-test.