Long-Term Repopulation Ability of Post–5-FU Recovering p53+/+ and p53−/− BMCs
| No. of Cells Injected . | No. of Survivors/Total . | ||
|---|---|---|---|
| Source of Cells: . | p53 +/+ . | p53 −/− . | |
| 105 | 4/10 | 8/10 | |
| 104 | 0/10 | 2/10 | |
| 103 | 0/10 | 0/10 | |
| No. of Cells Injected . | No. of Survivors/Total . | ||
|---|---|---|---|
| Source of Cells: . | p53 +/+ . | p53 −/− . | |
| 105 | 4/10 | 8/10 | |
| 104 | 0/10 | 2/10 | |
| 103 | 0/10 | 0/10 | |
TBI-treated recipient mice were injected IV with the indicated numbers of p53−/− or p53+/+ BMCs collected on day 6 after 5-FU treatment. Survival was scored 16 weeks later. Results represent two independent experiments.