PS Exposure in Normal and Thalassamic RBC
| Mutation . | AV Binding (%) . | ±SD . | n . |
|---|---|---|---|
| Normal control | 0.26 | 0.20 | 42 |
| HbH | 0.53 | 0.60 | 17 |
| HbH/CS | 1.00 | 1.66 | 16 |
| HbH/CS, splenectomized | 1.11 | 1 | |
| HbCS/CS | 0.85 | 0.61 | 5 |
| HbE/β-thal | 0.45 | 0.37 | 10 |
| HbE/β-thal, splenectomized | 9.5 | 7.5 | 4 |
| β-thal intermedia | 0.07 | 1 | |
| β-thal intermedia splenectomized | 3.4 | 3.7 | 2 |
| All thalassemic cells | 1.42 | 1.01 | 56 |
| Mutation . | AV Binding (%) . | ±SD . | n . |
|---|---|---|---|
| Normal control | 0.26 | 0.20 | 42 |
| HbH | 0.53 | 0.60 | 17 |
| HbH/CS | 1.00 | 1.66 | 16 |
| HbH/CS, splenectomized | 1.11 | 1 | |
| HbCS/CS | 0.85 | 0.61 | 5 |
| HbE/β-thal | 0.45 | 0.37 | 10 |
| HbE/β-thal, splenectomized | 9.5 | 7.5 | 4 |
| β-thal intermedia | 0.07 | 1 | |
| β-thal intermedia splenectomized | 3.4 | 3.7 | 2 |
| All thalassemic cells | 1.42 | 1.01 | 56 |
AV-FITC labeling of normal controls (fresh and travel controls) and patient samples. Indicated is the percentage of cells in the population that were labeled with AV-FITC above background as indicated in Fig 1.