Table 1. Expression of Human F.IX in... | American Society of Hematology

Table 1.

Expression of Human F.IX in CD-1 Mice After Intravenous Injection of AAV-CMV-F.IX at Day 1 of Life

Days Postinjection	Expression of hF.IX in Plasma (ng/mL)^-150	% Hepatocytes Expressing hF.IX^-151
5	77 (±24)	3 (±0.6)
14	15 (±6)	1.3 (±0.5)
35	2 (±3.5)	ND
60	0	ND
240-300	0	0.25 (±0.1)

Days Postinjection	Expression of hF.IX in Plasma (ng/mL)^-150	% Hepatocytes Expressing hF.IX^-151
5	77 (±24)	3 (±0.6)
14	15 (±6)	1.3 (±0.5)
35	2 (±3.5)	ND
60	0	ND
240-300	0	0.25 (±0.1)

Animals were killed at day 5 (n = 3), day 14 (n = 2), and day 240-300 (n = 8).

Abbreviation: ND, not determined.

As determined by ELISA.

As determined by image analysis of immunofluorescent staining of tissue sections.