Effect of Anti–P-Selectin Antibody on IRBC Rolling and Adhesion to Activated Platelets
| Isolate . | Rolling IRBC/min/mm2 . | Adherent IRBC/min/mm2 . | ||||
|---|---|---|---|---|---|---|
| NRS . | Anti–P-Selectin . | % Inhibition (SD) . | NRS . | Anti–P-Selectin . | % Inhibition (SD) . | |
| Responders | ||||||
| 96-12 | 94, 128 | 75, 89 | 25 (7) | 99, 85 | 57, 59 | 40 (12) |
| 96-26 | 118, 97 | 93, 76 | 21 (1) | 81, 93 | 66, 77 | 18 (1) |
| 96-32 | 123, 91 | 90, 69 | 26 (2) | 81, 102 | 42, 72 | 39 (13) |
| Nonresponders | ||||||
| 96-14 | 73, 95 | 80, 92 | 69, 52 | 71, 58 | ||
| 96-34 | 309, 291 | 298, 295 | 239, 260 | 287, 271 | ||
| 96-39 | 264, 231 | 264, 259 | 125, 103 | 154, 137 | ||
| Isolate . | Rolling IRBC/min/mm2 . | Adherent IRBC/min/mm2 . | ||||
|---|---|---|---|---|---|---|
| NRS . | Anti–P-Selectin . | % Inhibition (SD) . | NRS . | Anti–P-Selectin . | % Inhibition (SD) . | |
| Responders | ||||||
| 96-12 | 94, 128 | 75, 89 | 25 (7) | 99, 85 | 57, 59 | 40 (12) |
| 96-26 | 118, 97 | 93, 76 | 21 (1) | 81, 93 | 66, 77 | 18 (1) |
| 96-32 | 123, 91 | 90, 69 | 26 (2) | 81, 102 | 42, 72 | 39 (13) |
| Nonresponders | ||||||
| 96-14 | 73, 95 | 80, 92 | 69, 52 | 71, 58 | ||
| 96-34 | 309, 291 | 298, 295 | 239, 260 | 287, 271 | ||
| 96-39 | 264, 231 | 264, 259 | 125, 103 | 154, 137 | ||