Table 2. Characteristics of CTL Lines... | American Society of Hematology

Table 2.

Characteristics of CTL Lines Generated From Patients With Hodgkin's Disease

Patient Status	% Specific Lysis			% Inhibition of Autologous LCL		Phenotype
Patient Status	Autologous LCL	MM-LCL	HSB-2	Class I	Class II	CD4⁺	CD8⁺	γδ
1, Relapse	78	7	34	49	20	3	92	0.2
2, Relapse	62	8	38	61	3	10	89	1
3, Relapse	22	21	77	0	55	19	55	5
4, Remission	65	8	24	57	8	5	84
5, Remission	17	18	66	0	46	86	2	0.4
5, Relapse	19	17	78	0	37
6, Relapse	36	12	52	22	17	2	58	59
8, Remission	58	0	21	62	21	5	82
12, Remission	43	9	29	51	0	17	60	67
13, Relapse	57	35	86	0¹	0¹	17	67	16
Median	43	9	38	22	17	10	67	5
Range	17-78	0-21	21-86			2-86	2-92	0.2-67
Normal donors23
Median	40	13	26			19	77	2
Range	12-88	0-67	21-86			2-98	3-99	0-34

Patient Status	% Specific Lysis			% Inhibition of Autologous LCL		Phenotype
Patient Status	Autologous LCL	MM-LCL	HSB-2	Class I	Class II	CD4⁺	CD8⁺	γδ
1, Relapse	78	7	34	49	20	3	92	0.2
2, Relapse	62	8	38	61	3	10	89	1
3, Relapse	22	21	77	0	55	19	55	5
4, Remission	65	8	24	57	8	5	84
5, Remission	17	18	66	0	46	86	2	0.4
5, Relapse	19	17	78	0	37
6, Relapse	36	12	52	22	17	2	58	59
8, Remission	58	0	21	62	21	5	82
12, Remission	43	9	29	51	0	17	60	67
13, Relapse	57	35	86	0¹	0¹	17	67	16
Median	43	9	38	22	17	10	67	5
Range	17-78	0-21	21-86			2-86	2-92	0.2-67
Normal donors23
Median	40	13	26			19	77	2
Range	12-88	0-67	21-86			2-98	3-99	0-34

Inhibition seen after depletion of CD16⁺ and CD56⁺ cells: see text and Fig 7.

Abbreviation: MM, mismatched.