Table 1. Baseline Characteristics in 50... | American Society of Hematology

Table 1.

Baseline Characteristics in 50 Evaluable Patients

Variable	Arm A n = 24	Arm B n = 26	All Patients n = 50	P Value
Age (yr)	69 ± 10	69 ± 9	69 ± 9	.92
Sex (M/F)	8/16	18/8	26/24	.01
RA	4	6	10
RARS	8	5	13	.5^*
RAEB	12	15	27
IPSS (low/Int 1/Int 2/high)^-151	4/10/7/2	7/9/7/0	11/19/14/2	.4
Disease duration (mos)	11.6 ± 11.7	8.1 ± 8.1	9.3 ± 9.8	.23
Prior RBC transfusions (yes/no)	17/7	18/8	35/15	.90
RBC transf. units/mo^-152	2.5 ± 1.1	2.9 ± 1.6	2.7 ± 1.4	.45
Hemoglobin level (g/dL)	87.0 ± 10.8	86.3 ± 12.8	86.4 ± 11.7	.85
ANC count × 10⁹/L	2.2 ± 1.9	2.1 ± 1.7	2.2 ± 1.8	.88
Platelet count × 10⁹/L	210 ± 141	216 ± 193	213 ± 168	.75
Bone marrow cellularity (%)	70 ± 24	78 ± 20	74 ± 22	.23
Bone marrow blasts (%)	7.0 ± 5.9	6.2 ± 3.9	6.6 ± 4.9	.58
Karyotype (normal/abnormal)	13/10	9/14	22/24	.5
Serum erythropoietin (U/L)^-153	216 (6-4979)	237 (20-4128)	216	.61
S. transferrin receptor (ng/mL)	6,983 ± 5,631	6,480 ± 5,987	6,714 ± 5,763	.77

Variable	Arm A n = 24	Arm B n = 26	All Patients n = 50	P Value
Age (yr)	69 ± 10	69 ± 9	69 ± 9	.92
Sex (M/F)	8/16	18/8	26/24	.01
RA	4	6	10
RARS	8	5	13	.5^*
RAEB	12	15	27
IPSS (low/Int 1/Int 2/high)^-151	4/10/7/2	7/9/7/0	11/19/14/2	.4
Disease duration (mos)	11.6 ± 11.7	8.1 ± 8.1	9.3 ± 9.8	.23
Prior RBC transfusions (yes/no)	17/7	18/8	35/15	.90
RBC transf. units/mo^-152	2.5 ± 1.1	2.9 ± 1.6	2.7 ± 1.4	.45
Hemoglobin level (g/dL)	87.0 ± 10.8	86.3 ± 12.8	86.4 ± 11.7	.85
ANC count × 10⁹/L	2.2 ± 1.9	2.1 ± 1.7	2.2 ± 1.8	.88
Platelet count × 10⁹/L	210 ± 141	216 ± 193	213 ± 168	.75
Bone marrow cellularity (%)	70 ± 24	78 ± 20	74 ± 22	.23
Bone marrow blasts (%)	7.0 ± 5.9	6.2 ± 3.9	6.6 ± 4.9	.58
Karyotype (normal/abnormal)	13/10	9/14	22/24	.5
Serum erythropoietin (U/L)^-153	216 (6-4979)	237 (20-4128)	216	.61
S. transferrin receptor (ng/mL)	6,983 ± 5,631	6,480 ± 5,987	6,714 ± 5,763	.77

*Step-wise ANOVA.

IPSS, International prognostic scoring system.2 Low, low risk; int-1, intermediate 1 risk; int-2, intermediate 2 risk; high, high risk.

Transfusion needed from 35 patients with pretreatment RBC transfusions.

Mann-Whitney U test.