Percentage of Apoptosis Induced by CD95 Cross-Linking, Irradiation, and Straurosporine Treatment of Lymphoma and Nontumoral B Cells
| Case . | CD95 Expression . | CD95 MoAb . | Irradiation . | Staurosporine . | |||
|---|---|---|---|---|---|---|---|
| 4 h . | 18 h . | 4 h . | 18 h . | 4 h . | 18 h . | ||
| Jurkat | 168 | 38 | 86 | 35 | 83 | 65 | 96 |
| NT-1 | 21 | ≤5 | ≤5 | 18 | 59 | 71 | 88 |
| NT-2 | 47 | ≤5 | ≤5 | 11 | 58 | 66 | 84 |
| NT-3 | 62 | ≤5 | ≤5 | 27 | 86 | 81 | 97 |
| LCL-1 | 9 | ≤5 | ≤5 | ≤5 | 52 | 76 | 95 |
| LCL-2 | 5 | ≤5 | ≤5 | ≤5 | 38 | 29 | 92 |
| LCL-3 | 30 | ≤5 | ≤5 | ND | ND | ND | ND |
| LCL-4 | 40 | ≤5 | ≤5 | ≤5 | 42 | 61 | 91 |
| MCL-1 | 14 | ≤5 | ≤5 | ND | ND | ND | ND |
| MCL-2 | 14 | ≤5 | ≤5 | ND | ND | ND | ND |
| MCL-3 | 9 | ≤5 | ≤5 | ≤5 | 36 | 61 | NC-150 |
| MCL-4 | 31 | ≤5 | ≤5 | 8 | 55 | 60 | NC |
| MCL-5 | 13 | ≤5 | ≤5 | 9 | 69 | 51 | NC |
| MCL-6 | 17 | ≤5 | ≤5 | ≤5 | 33 | 88 | 98 |
| FL-1 | 34 | ≤5 | 8 | ≤5 | 58 | 35 | 97 |
| FL-2 | 34 | ≤5 | ≤5 | ≤5 | 59 | 30 | 82 |
| FL-3 | 59 | ≤5 | ≤5 | ≤5 | 20 | 24 | 87 |
| FL-4 | 42 | ≤5 | ≤5 | 7 | 44 | 10 | 69 |
| FL-5 | 88 | ≤5 | 7 | ≤5 | 20 | 40 | 68 |
| FL-6 | 86 | ND | ND | ≤5 | 35 | 16 | 84 |
| DLCL-1 | 48 | ≤5 | ≤5 | ND | ND | ND | ND |
| DLCL-2 | 15 | ≤5 | ≤5 | ≤5 | 22 | 39 | 84 |
| DLCL-3 | 38 | ≤5 | ≤5 | ≤5 | 13 | ≤5 | 24 |
| DLCL-4 | 198 | ≤5 | ≤5 | ≤5 | 28 | 8 | 81 |
| Case . | CD95 Expression . | CD95 MoAb . | Irradiation . | Staurosporine . | |||
|---|---|---|---|---|---|---|---|
| 4 h . | 18 h . | 4 h . | 18 h . | 4 h . | 18 h . | ||
| Jurkat | 168 | 38 | 86 | 35 | 83 | 65 | 96 |
| NT-1 | 21 | ≤5 | ≤5 | 18 | 59 | 71 | 88 |
| NT-2 | 47 | ≤5 | ≤5 | 11 | 58 | 66 | 84 |
| NT-3 | 62 | ≤5 | ≤5 | 27 | 86 | 81 | 97 |
| LCL-1 | 9 | ≤5 | ≤5 | ≤5 | 52 | 76 | 95 |
| LCL-2 | 5 | ≤5 | ≤5 | ≤5 | 38 | 29 | 92 |
| LCL-3 | 30 | ≤5 | ≤5 | ND | ND | ND | ND |
| LCL-4 | 40 | ≤5 | ≤5 | ≤5 | 42 | 61 | 91 |
| MCL-1 | 14 | ≤5 | ≤5 | ND | ND | ND | ND |
| MCL-2 | 14 | ≤5 | ≤5 | ND | ND | ND | ND |
| MCL-3 | 9 | ≤5 | ≤5 | ≤5 | 36 | 61 | NC-150 |
| MCL-4 | 31 | ≤5 | ≤5 | 8 | 55 | 60 | NC |
| MCL-5 | 13 | ≤5 | ≤5 | 9 | 69 | 51 | NC |
| MCL-6 | 17 | ≤5 | ≤5 | ≤5 | 33 | 88 | 98 |
| FL-1 | 34 | ≤5 | 8 | ≤5 | 58 | 35 | 97 |
| FL-2 | 34 | ≤5 | ≤5 | ≤5 | 59 | 30 | 82 |
| FL-3 | 59 | ≤5 | ≤5 | ≤5 | 20 | 24 | 87 |
| FL-4 | 42 | ≤5 | ≤5 | 7 | 44 | 10 | 69 |
| FL-5 | 88 | ≤5 | 7 | ≤5 | 20 | 40 | 68 |
| FL-6 | 86 | ND | ND | ≤5 | 35 | 16 | 84 |
| DLCL-1 | 48 | ≤5 | ≤5 | ND | ND | ND | ND |
| DLCL-2 | 15 | ≤5 | ≤5 | ≤5 | 22 | 39 | 84 |
| DLCL-3 | 38 | ≤5 | ≤5 | ≤5 | 13 | ≤5 | 24 |
| DLCL-4 | 198 | ≤5 | ≤5 | ≤5 | 28 | 8 | 81 |
CD95 expression is expressed in MFI values.
Abbreviations: ND, not done; NC, not calculated.
Percentage of apoptotic cells was not calculated when the total number of dead cells in control was greater than 60%.