F. IX Coagulant Assays in Normal, Carrier Female, and Affected Male Mice
Sample . | No. . | Factor IX Coagulant Titer, U/dL . | |
---|---|---|---|
Mean ± SD . | Range . | ||
Normal (males and females) | 22 | 92.0 ± 30.0 | 60-165 |
Normal females | 9 | 69.0 ± 15.9 | 60-97 |
Carrier females | 14 | 35.0 ± 7.9 | 26-49 |
Affected males | 10 | 2.8 ± 1.5 | <1-63-150 |
Sample . | No. . | Factor IX Coagulant Titer, U/dL . | |
---|---|---|---|
Mean ± SD . | Range . | ||
Normal (males and females) | 22 | 92.0 ± 30.0 | 60-165 |
Normal females | 9 | 69.0 ± 15.9 | 60-97 |
Carrier females | 14 | 35.0 ± 7.9 | 26-49 |
Affected males | 10 | 2.8 ± 1.5 | <1-63-150 |
Abbreviation: SD, standard deviation.
Although appropriate care was taken to obtain freely flowing blood, the coagulant activity detected may reflect the activation of the coagulation cascade during blood collection from contamination with tissue fluid.