Table 4.

F. IX Coagulant Assays in Normal, Carrier Female, and Affected Male Mice

Sample No. Factor IX Coagulant Titer, U/dL
Mean ± SD Range
Normal (males and females)  22  92.0 ± 30.0  60-165  
Normal females  69.0 ± 15.9  60-97  
Carrier females  14 35.0 ± 7.9  26-49  
Affected males  10 2.8 ± 1.5  <1-63-150 
Sample No. Factor IX Coagulant Titer, U/dL
Mean ± SD Range
Normal (males and females)  22  92.0 ± 30.0  60-165  
Normal females  69.0 ± 15.9  60-97  
Carrier females  14 35.0 ± 7.9  26-49  
Affected males  10 2.8 ± 1.5  <1-63-150 

Abbreviation: SD, standard deviation.

F3-150

Although appropriate care was taken to obtain freely flowing blood, the coagulant activity detected may reflect the activation of the coagulation cascade during blood collection from contamination with tissue fluid.

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