Characteristics of the Patients, Serum Monoclonal Ig, and Detection of Virus (KSHV/HHV-8) DNA and Antibodies
| Patient No. . | Age (yr)/ Sex . | Diagnosis and Clinical Stage . | Monoclonal Ig . | Monoclonal Ig Concentration (g/L) . | PCR* (KSHV/ HHV8) . | Serological Study-151 . |
|---|---|---|---|---|---|---|
| 1 | 66/M | MGUS | IgG1κ | 20 | — | — |
| 2 | 50/F | MGUS | IgG4λ | 19 | — | — |
| 3 | 68/F | MM, IA | IgG1κ | 30 | — | — |
| 4 | 54/M | MM, IA | IgG1κ | 25 | — | — |
| 5 | 36/M | MM, IIA | IgG1λ | 41 | — | — |
| 6 | 76/M | MM, IIA | IgAκ | 26 | — | — |
| 7 | 68/M | MM IIA | IgAκ | 38 | — | — |
| 8 | 51/F | MM, IIIA | IgG | 58 | — | — |
| 9 | 54/M | MM, IIIA | Nonsecretory | — | — | — |
| 10 | 62/F | MM, IIIA | IgAκ | 25 | — | — |
| Patient No. . | Age (yr)/ Sex . | Diagnosis and Clinical Stage . | Monoclonal Ig . | Monoclonal Ig Concentration (g/L) . | PCR* (KSHV/ HHV8) . | Serological Study-151 . |
|---|---|---|---|---|---|---|
| 1 | 66/M | MGUS | IgG1κ | 20 | — | — |
| 2 | 50/F | MGUS | IgG4λ | 19 | — | — |
| 3 | 68/F | MM, IA | IgG1κ | 30 | — | — |
| 4 | 54/M | MM, IA | IgG1κ | 25 | — | — |
| 5 | 36/M | MM, IIA | IgG1λ | 41 | — | — |
| 6 | 76/M | MM, IIA | IgAκ | 26 | — | — |
| 7 | 68/M | MM IIA | IgAκ | 38 | — | — |
| 8 | 51/F | MM, IIIA | IgG | 58 | — | — |
| 9 | 54/M | MM, IIIA | Nonsecretory | — | — | — |
| 10 | 62/F | MM, IIIA | IgAκ | 25 | — | — |
*Primer pairs KS-1,2. DNA extracted from adherent cells cultured for 7 days with GM-CSF and IL-4 as previously described.9
An IFA assay was used based on cultured BCBL cells.11 All sera were taken at the same time as the cell preparation.