TRAP-14 Induces CD106 Expression
Conditions . | 6 h (% of positive cells) . | 24 h (% of positive cells) . |
---|---|---|
Control | 6.6 ± 2 | 2 ± 1 |
Thrombin | 47 ± 3.43-150 | 12.7 ± 33-151 |
TRAP-14 | 51 ± 23-150 | 9 ± 1 |
Control peptide | 3.3 ± 0.3 | 6 ± 2 |
Conditions . | 6 h (% of positive cells) . | 24 h (% of positive cells) . |
---|---|---|
Control | 6.6 ± 2 | 2 ± 1 |
Thrombin | 47 ± 3.43-150 | 12.7 ± 33-151 |
TRAP-14 | 51 ± 23-150 | 9 ± 1 |
Control peptide | 3.3 ± 0.3 | 6 ± 2 |
HUVECs were cultured in the presence of thrombin (8 U/mL), TRAP-14, or the control peptide (100 μmol/L) for 6 or 24 hours. After cell trypsinization, CD106 expression on HUVECs was studied by FACS analysis.
P < .005 compared with respective controls (n = 3).
P < .05 compared with respective controls (n = 3).