Distribution of FcγRIIa Genotypes and Allele Frequencies in HIT Patients and Controls
| . | n . | FcγRIIa Allele Frequency . | FcγRIIa Genotype* . | . | ||||
|---|---|---|---|---|---|---|---|---|
| R131 . | H131 . | R/R131 . | R/H131 . | H/H131 . | . | |||
| HIT patients | 389 | 0.54 | 0.46 | 105 (27.0) | 207 (53.2) | 77 (19.8) | P < .001-151 | |
| Non-HIT patients | 351 | 0.45 | 0.55 | 74 (21.1) | 166 (47.3) | 111 (31.6) | P = .45-151 | P = .024-151 |
| Healthy blood donors | 256 | 0.46 | 0.54 | 51 (19.9) | 134 (52.4) | 71 (27.7) | ||
| . | n . | FcγRIIa Allele Frequency . | FcγRIIa Genotype* . | . | ||||
|---|---|---|---|---|---|---|---|---|
| R131 . | H131 . | R/R131 . | R/H131 . | H/H131 . | . | |||
| HIT patients | 389 | 0.54 | 0.46 | 105 (27.0) | 207 (53.2) | 77 (19.8) | P < .001-151 | |
| Non-HIT patients | 351 | 0.45 | 0.55 | 74 (21.1) | 166 (47.3) | 111 (31.6) | P = .45-151 | P = .024-151 |
| Healthy blood donors | 256 | 0.46 | 0.54 | 51 (19.9) | 134 (52.4) | 71 (27.7) | ||
*Values are the number of patients with the percentage in parentheses.
P values are calculated for FcγRIIa-R/R131, −R/H131, and −H/H131 genotype differences by χ2 test for contingency tables with 2 × 3 fields.