Table 2.

Effect of Aspirin and Ticlopidine on Platelet Aggregation

% ADP (μmol/L)Collagen (μg/mL) Arachidonic Acid (mmol/L)
2.5 5 3.3 10 1
Placebo 36 ± 5  49 ± 3  59 ± 2 60 ± 2  49 ± 4  
Aspirin  25 ± 3  42 ± 2 30 ± 2* 51 ± 2* 2 ± 1* 
Ticlopidine 13 ± 2* 23 ± 4* 54 ± 3  60 ± 2 40 ± 5  
Aspirin + ticlopidine  12 ± 1* 20 ± 2* 16 ± 3* 34 ± 2* 1 ± 1* 
% ADP (μmol/L)Collagen (μg/mL) Arachidonic Acid (mmol/L)
2.5 5 3.3 10 1
Placebo 36 ± 5  49 ± 3  59 ± 2 60 ± 2  49 ± 4  
Aspirin  25 ± 3  42 ± 2 30 ± 2* 51 ± 2* 2 ± 1* 
Ticlopidine 13 ± 2* 23 ± 4* 54 ± 3  60 ± 2 40 ± 5  
Aspirin + ticlopidine  12 ± 1* 20 ± 2* 16 ± 3* 34 ± 2* 1 ± 1* 

Results are expressed as % of the maximal amplitude of the platelet aggregation curve.

*

P < .01 versus placebo.

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