GPI-Linked (CD59/CD48) Antigen Expression by Lymphocyte Subpopulations
| . | CD3+ (T Cells) % GPI− . | CD4+ (T Helper) % GPI− . | CD8+ (T Cytotoxic) % GPI− . | CD19+ (B Cells) % GPI− . | CD3−CD16+ (NK Cells) % GPI− . |
|---|---|---|---|---|---|
| Patient ID | |||||
| PNH003 | 0.2 | nt | nt | 1.4 | 4.5 |
| PNH008 | 20.8 | 23.5 | 22.2 | 23.8 | 14.7 |
| PNH012 | 21.6 | 21.3 | 32.3 | 11.8 | 64.6 |
| PNH019 | 12.6 | 10.7 | 12.6 | 1.1 | 12.9 |
| PNH020 | 16.8 | 16.2 | 18.2 | 9.3 | 95.1 |
| PNH022 | 7.8 | 7.9 | 11.1 | 9.9 | 36.8 |
| PNH030 | 9.4 | 14.0 | 4.3 | 5.8 | 0.7 |
| PNH033 | 21.3 | 21.7 | 20.7 | 36.6 | nt |
| PNH034 | 1.9 | 1.4 | 3.2 | 47.8 | 75.8 |
| PNH042 | 1.9 | 1.1 | 2.7 | 0.8 | 36.1 |
| PNH043 | 5.0 | 5.9 | 4.4 | 2.9 | 12.1 |
| PNH047 | 0.0 | 0.0 | 0.0 | 0.0 | 14.00 |
| PNH048 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| PNH058 | 6.8 | 6.1 | 8.6 | 1.3 | 73.9 |
| PNH061 | 0.0 | 0.0 | 0.0 | 20.93-150 | 9.23-150 |
| PNH063 | 8.13-150 | 9.63-150 | 10.43-150 | 25.53-150 | 38.93-150 |
| PNH064 | 0.5 | nt | nt | nt | 0.12 |
| PNH072 | 16.0 | 15.9 | 26.0 | 17.4 | 74.0 |
| PNH079 | 17.8 | 17.2 | 20.7 | 58.9 | 85.2 |
| . | CD3+ (T Cells) % GPI− . | CD4+ (T Helper) % GPI− . | CD8+ (T Cytotoxic) % GPI− . | CD19+ (B Cells) % GPI− . | CD3−CD16+ (NK Cells) % GPI− . |
|---|---|---|---|---|---|
| Patient ID | |||||
| PNH003 | 0.2 | nt | nt | 1.4 | 4.5 |
| PNH008 | 20.8 | 23.5 | 22.2 | 23.8 | 14.7 |
| PNH012 | 21.6 | 21.3 | 32.3 | 11.8 | 64.6 |
| PNH019 | 12.6 | 10.7 | 12.6 | 1.1 | 12.9 |
| PNH020 | 16.8 | 16.2 | 18.2 | 9.3 | 95.1 |
| PNH022 | 7.8 | 7.9 | 11.1 | 9.9 | 36.8 |
| PNH030 | 9.4 | 14.0 | 4.3 | 5.8 | 0.7 |
| PNH033 | 21.3 | 21.7 | 20.7 | 36.6 | nt |
| PNH034 | 1.9 | 1.4 | 3.2 | 47.8 | 75.8 |
| PNH042 | 1.9 | 1.1 | 2.7 | 0.8 | 36.1 |
| PNH043 | 5.0 | 5.9 | 4.4 | 2.9 | 12.1 |
| PNH047 | 0.0 | 0.0 | 0.0 | 0.0 | 14.00 |
| PNH048 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| PNH058 | 6.8 | 6.1 | 8.6 | 1.3 | 73.9 |
| PNH061 | 0.0 | 0.0 | 0.0 | 20.93-150 | 9.23-150 |
| PNH063 | 8.13-150 | 9.63-150 | 10.43-150 | 25.53-150 | 38.93-150 |
| PNH064 | 0.5 | nt | nt | nt | 0.12 |
| PNH072 | 16.0 | 15.9 | 26.0 | 17.4 | 74.0 |
| PNH079 | 17.8 | 17.2 | 20.7 | 58.9 | 85.2 |
CD48/CD59 expression determined by -color flow cytometry as described in Materials and Methods.
Abbreviation: nt, not tested.
Partial deficiency of CD48/CD59 GPI-linked antigens.