Antibodies Used to Probe srGPIIb-IIIa
| Name . | Type-150 . | Specificity . | Source . |
|---|---|---|---|
| Tab | IgG2a MoAb | GPIIb | R. McEver |
| MBC132.1 | IgG1 MoAb | GPIIb | BCSEW |
| B1B5 | IgG1 MoAb | GPIIb light chain | J. Bennet |
| AP3 | IgG1 MoAb | GPIIIa (348-421) | P.J. Newman |
| AP5 | IgG1 MoAb | GPIIIa (1-6) (LIBS) | T.J. Kunicki |
| AP6 | IgM MoAb | GPIIIa (211-221) | T.J. Kunicki |
| D3 | IgG1 MoAb | GPIIIa (422-490) (LIBS) | L. Jennings |
| CRC54 | IgG1 MoAb | GPIIIa (1-100) LIBS | M.J. Berndt |
| Fire/Ice | Rabbit | GPIIIa | P.J. Newman |
| AP2 | IgG1 MoAb | GPIIb-IIIa complex | T.J. Kunicki |
| 10E5 | IgG2a MoAb | GPIIb-IIIa complex | B. Coller |
| 7E3 | IgG1 MoAb | GPIIb-IIIa complex | B. Coller |
| PAC-1 | IgM MoAb | GPIIb-IIIa ligand mimetic | S. Shattil |
| KR | Human allo-Ab | P1A1 (HPA-1a) | BCSEW |
| TR | Human allo-Ab | Pena (HPA-4b) | BCSEW |
| KE | Human allo-Ab | Baka (HPA-3a) | BCSEW |
| LB | Human AITP | GPIIIa | BCSEW |
| JN | Human AITP | GPIIIa | BCSEW |
| MD | Human AITP | GPIIb-IIIa complex | BCSEW |
| MA | Human quinine DDAb | GPIIIa | BCSEW |
| JW | Human quinine DDAb | GPIIIa | BCSEW |
| RB | Human quinine DDAb | GPIIIa | BCSEW |
| GW | Human quinidine DDAb | GPIIIa + GPIIb-IIIa complex | BCSEW |
| BC | Human SMX DDAb | GPIIb-IIIa complex | BCSEW |
| TB | Human SMX DDAb | GPIIb-IIIa complex | BCSEW |
| Name . | Type-150 . | Specificity . | Source . |
|---|---|---|---|
| Tab | IgG2a MoAb | GPIIb | R. McEver |
| MBC132.1 | IgG1 MoAb | GPIIb | BCSEW |
| B1B5 | IgG1 MoAb | GPIIb light chain | J. Bennet |
| AP3 | IgG1 MoAb | GPIIIa (348-421) | P.J. Newman |
| AP5 | IgG1 MoAb | GPIIIa (1-6) (LIBS) | T.J. Kunicki |
| AP6 | IgM MoAb | GPIIIa (211-221) | T.J. Kunicki |
| D3 | IgG1 MoAb | GPIIIa (422-490) (LIBS) | L. Jennings |
| CRC54 | IgG1 MoAb | GPIIIa (1-100) LIBS | M.J. Berndt |
| Fire/Ice | Rabbit | GPIIIa | P.J. Newman |
| AP2 | IgG1 MoAb | GPIIb-IIIa complex | T.J. Kunicki |
| 10E5 | IgG2a MoAb | GPIIb-IIIa complex | B. Coller |
| 7E3 | IgG1 MoAb | GPIIb-IIIa complex | B. Coller |
| PAC-1 | IgM MoAb | GPIIb-IIIa ligand mimetic | S. Shattil |
| KR | Human allo-Ab | P1A1 (HPA-1a) | BCSEW |
| TR | Human allo-Ab | Pena (HPA-4b) | BCSEW |
| KE | Human allo-Ab | Baka (HPA-3a) | BCSEW |
| LB | Human AITP | GPIIIa | BCSEW |
| JN | Human AITP | GPIIIa | BCSEW |
| MD | Human AITP | GPIIb-IIIa complex | BCSEW |
| MA | Human quinine DDAb | GPIIIa | BCSEW |
| JW | Human quinine DDAb | GPIIIa | BCSEW |
| RB | Human quinine DDAb | GPIIIa | BCSEW |
| GW | Human quinidine DDAb | GPIIIa + GPIIb-IIIa complex | BCSEW |
| BC | Human SMX DDAb | GPIIb-IIIa complex | BCSEW |
| TB | Human SMX DDAb | GPIIb-IIIa complex | BCSEW |
Abbreviations: LIBS, ligand-induced binding site; SMX, sulfamethoxazole; AITP, autoimmune thrombocytopenic purpura; DDAb, drug-dependent antibody; BCSEW, Blood Center of Southeastern Wisconsin.
Antibodies are murine monoclonals, unless otherwise stated.