Inhibitory Effect of IL-10 on Autonomous BFU-E Growth in PV Patients
| Patient . | MNC/Dish × 103 . | BFU-E ± SD/Dish . | Percent of Inhibition . | P . | |
|---|---|---|---|---|---|
| Control . | +IL-10 . | ||||
| HR | 100 | 32.0 ± 3.5 | 9.3 ± 1.2 | 71 | <.001 |
| KJ | 100 | 43.0 ± 1.7 | 10.3 ± 1.5 | 76 | <.001 |
| KA | 100 | 5.0 ± 1.0 | 0.3 ± 0.6 | 94 | <.005 |
| JP | 116 | 15.8 ± 4.2 | 3.0 ± 0.0 | 81 | <.05 |
| SA | 75 | 107.3 ± 7.6 | 19.3 ± 2.5 | 82 | <.001 |
| Patient . | MNC/Dish × 103 . | BFU-E ± SD/Dish . | Percent of Inhibition . | P . | |
|---|---|---|---|---|---|
| Control . | +IL-10 . | ||||
| HR | 100 | 32.0 ± 3.5 | 9.3 ± 1.2 | 71 | <.001 |
| KJ | 100 | 43.0 ± 1.7 | 10.3 ± 1.5 | 76 | <.001 |
| KA | 100 | 5.0 ± 1.0 | 0.3 ± 0.6 | 94 | <.005 |
| JP | 116 | 15.8 ± 4.2 | 3.0 ± 0.0 | 81 | <.05 |
| SA | 75 | 107.3 ± 7.6 | 19.3 ± 2.5 | 82 | <.001 |
PBMNCs from PV patients were cultured as described in the Materials and Methods with or without 10 ng/mL IL-10. Colony growth was assessed after 14 days. Results represent mean values ± SD from triplicates.