Patient Characteristics
Variables-150 . | No G-CSF (n = 115) . | G-CSF (n = 81) . | P Value . |
---|---|---|---|
Year of transplant | 1990-1993 | 1994-1996 | |
Median patient age, yr (range) | 40 (18-59) | 43 (21-61) | .09 |
Median donor age, yr (range) | 38 (16-57) | 42 (16-71) | .17 |
Gender (donor/patient) | .41 | ||
Female/male | 32 (28%) | 14 (17%) | |
All other combinations | 83 (72%) | 67 (83%) | |
Advanced disease, no. (%) | 68 (59%) | 54 (67%) | .24 |
Heavily pretreated, no. (%) | 80 (70%) | 61 (75%) | .38 |
CMV status (donor/patient) | .03 | ||
Neg/Neg | 38 (34%) | 40 (51%) | |
All other combinations | 74 (66%) | 39 (49%) | |
Stem cell dose-151 (range) | 5.8 (1.7-15) | 4.8 (1.3-20) | .004 |
Total body irradiation | <.0001 | ||
1,400 rads | 104 (90%) | 14 (17%) | |
1,480 rads | 11 (10%) | 30 (37%) | |
1,560 rads | 0 | 37 (46%) |
Variables-150 . | No G-CSF (n = 115) . | G-CSF (n = 81) . | P Value . |
---|---|---|---|
Year of transplant | 1990-1993 | 1994-1996 | |
Median patient age, yr (range) | 40 (18-59) | 43 (21-61) | .09 |
Median donor age, yr (range) | 38 (16-57) | 42 (16-71) | .17 |
Gender (donor/patient) | .41 | ||
Female/male | 32 (28%) | 14 (17%) | |
All other combinations | 83 (72%) | 67 (83%) | |
Advanced disease, no. (%) | 68 (59%) | 54 (67%) | .24 |
Heavily pretreated, no. (%) | 80 (70%) | 61 (75%) | .38 |
CMV status (donor/patient) | .03 | ||
Neg/Neg | 38 (34%) | 40 (51%) | |
All other combinations | 74 (66%) | 39 (49%) | |
Stem cell dose-151 (range) | 5.8 (1.7-15) | 4.8 (1.3-20) | .004 |
Total body irradiation | <.0001 | ||
1,400 rads | 104 (90%) | 14 (17%) | |
1,480 rads | 11 (10%) | 30 (37%) | |
1,560 rads | 0 | 37 (46%) |