Table 2. Clinical and Echocardiographic... | American Society of Hematology

Table 2.

Clinical and Echocardiographic Characteristics of Patients With β-Thalassemia Major

	Group A (n = 151)	Group B (n = 53)	Group C (n = 47)
Symptoms
Asymptomatic	151	53	0
NYHA I-II	0	0	19
NYHA III-IV	0	0	28
Echocardiographic measurements (mean ± 1 SD)
M-mode
LVEDDI^*	26 ± 4	35 ± 3	37 ± 4
LVDD^*	47 ± 8	56 ± 5	58 ± 7
LVDS^†	29 ± 4	38 ± 4	48 ± 5
FS^‡	38 ± 6	33 ± 4	17 ± 6
IVS thickness^1-153	8.5 ± 1.7	8.4 ± 1.7	8.4 ± 1.6
LVPW thickness^1-153	8.4 ± 1.4	8.4 ± 1.3	8.4 ± 1.2
RVD^1-153	19 ± 4	19 ± 5	21 ± 3
LA^*	33 ± 6	39 ± 4	40 ± 8
Two-dimensional
EF^‡	61 ± 9	55 ± 5	30 ± 11

	Group A (n = 151)	Group B (n = 53)	Group C (n = 47)
Symptoms
Asymptomatic	151	53	0
NYHA I-II	0	0	19
NYHA III-IV	0	0	28
Echocardiographic measurements (mean ± 1 SD)
M-mode
LVEDDI^*	26 ± 4	35 ± 3	37 ± 4
LVDD^*	47 ± 8	56 ± 5	58 ± 7
LVDS^†	29 ± 4	38 ± 4	48 ± 5
FS^‡	38 ± 6	33 ± 4	17 ± 6
IVS thickness^1-153	8.5 ± 1.7	8.4 ± 1.7	8.4 ± 1.6
LVPW thickness^1-153	8.4 ± 1.4	8.4 ± 1.3	8.4 ± 1.2
RVD^1-153	19 ± 4	19 ± 5	21 ± 3
LA^*	33 ± 6	39 ± 4	40 ± 8
Two-dimensional
EF^‡	61 ± 9	55 ± 5	30 ± 11

Abbreviations: LVEDDI, left ventricular end diastolic diameter index (mm/m²); LVDD, left ventricular diastolic diameter (mm); LVDS, left ventricular systolic diameter (mm); FS, left ventricular fractional shortening (%); IVS, interventricular septum (mm); LVPW, left ventricular posterior wall (mm); RVD, right ventricular diameter (mm); LA, left atrial diameter (mm); EF, left ventricular ejection fraction (%).

P < .05 group A v group B, nonsignificant group B v group C.

†

P < .05 group A v group B and group Bv group C.

‡

Nonsignificant group A v group B, P < .05 group B v group C.

F1-153

Not significantly different between the three subgroups.

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