Table 1. Effect of 2.4G2 on... | American Society of Hematology

Table 1.

Effect of 2.4G2 on B-Lymphopoiesis in C57BL6/129^+/+, CD16^−/−, and CD32^−/−

	Fresh Bone Marrow		Bone Marrow Culture at 72 h
	Fresh Bone Marrow		Cytokines		Cytokines +2.4G2
	No.	%^-150	Total No.	%	Total No.	%
B220⁺ cells
wt^+/+	22,000 ± 9,200	32 ± 3	33,285 ± 8,741	43 ± 3	48,000 ± 3,390	48 ± 4
CD16^−/−	26,414 ± 13,480	38 ± 6	14,538 ± 3,800^-151	49 ± 11	16,071 ± 1,739^-152	47 ± 10
CD32^−/−	43,950 ± 11,855^-151	40 ± 14	28,923 ± 5,519	28 ± 6	23,259 ± 12,419	28 ± 9
B220⁺/IgM⁺ cells
wt^+/+	6,893 ± 3,378	12 ± 2	21,895 ± 6,159	34 ± 4	30,255 ± 3,331	39 ± 5
CD16^−/−	6,437 ± 2,163	10 ± 0.2	8,511 ± 1,131^-151	34 ± 3	10,240 ± 814^-152	36 ± 6
CD32^−/−	16,755 ± 4,391^-151	19 ± 8	18,193 ± 3,325	16 ± 5	14,308 ± 8,530	16 ± 6

	Fresh Bone Marrow		Bone Marrow Culture at 72 h
	Fresh Bone Marrow		Cytokines		Cytokines +2.4G2
	No.	%^-150	Total No.	%	Total No.	%
B220⁺ cells
wt^+/+	22,000 ± 9,200	32 ± 3	33,285 ± 8,741	43 ± 3	48,000 ± 3,390	48 ± 4
CD16^−/−	26,414 ± 13,480	38 ± 6	14,538 ± 3,800^-151	49 ± 11	16,071 ± 1,739^-152	47 ± 10
CD32^−/−	43,950 ± 11,855^-151	40 ± 14	28,923 ± 5,519	28 ± 6	23,259 ± 12,419	28 ± 9
B220⁺/IgM⁺ cells
wt^+/+	6,893 ± 3,378	12 ± 2	21,895 ± 6,159	34 ± 4	30,255 ± 3,331	39 ± 5
CD16^−/−	6,437 ± 2,163	10 ± 0.2	8,511 ± 1,131^-151	34 ± 3	10,240 ± 814^-152	36 ± 6
CD32^−/−	16,755 ± 4,391^-151	19 ± 8	18,193 ± 3,325	16 ± 5	14,308 ± 8,530	16 ± 6

P values were calculated by comparison with the wild-type.

Percentage of the lymphoid gate.

P < .05.

P < .001.