Effect of IL-7 and 2.4G2 on B-Lymphopoiesis in C57BL6/129
| . | Total No. of B220+ Cells . | No. of B220+/IgM+ Cells . |
|---|---|---|
| −IL-7 | ||
| Control* | 30,831 ± 9,302 | 18,197 ± 4,570 |
| +2.4G2 | 44,737 ± 13,804 | 27,774 ± 10,259 |
| (1.54 SI) | (1.52 SI) | |
| +IL-7 | ||
| Control* | 99,560 ± 11,623 | 44,045 ± 6,448 |
| +2.4G2 | 128,660 ± 5,006 | 60,295 ± 3,867 |
| (1.29 SI) | (1.36 SI) |
| . | Total No. of B220+ Cells . | No. of B220+/IgM+ Cells . |
|---|---|---|
| −IL-7 | ||
| Control* | 30,831 ± 9,302 | 18,197 ± 4,570 |
| +2.4G2 | 44,737 ± 13,804 | 27,774 ± 10,259 |
| (1.54 SI) | (1.52 SI) | |
| +IL-7 | ||
| Control* | 99,560 ± 11,623 | 44,045 ± 6,448 |
| +2.4G2 | 128,660 ± 5,006 | 60,295 ± 3,867 |
| (1.29 SI) | (1.36 SI) |
Values were determined after 72 hours of culture using the cytokines and conditions described in the text.
Abbreviation: SI, stimulation index.
In some experiments, control cultures contained isotype-matched rat antibody of irrelevant specificity; in others, antibody was omitted.