Effect of 2.4G2 on Purified Progenitor B Cells (B220+, IgM−) Cocultured With Bone Marrow Stromal Cells (BMS2) for 72 Hours
| Source of Progenitor B Cells . | 2.4G2 Added . | % HSAlo . | MFI . | %IgM+ . | MFI . |
|---|---|---|---|---|---|
| wt+/+ | No | 75 ± 13 | 77 ± 9 | 58 ± 6 | 127 ± 4 |
| Yes | 73 ± 17 | 81 ± 10 | 76 ± 7 | 140 ± 7 | |
| P = .014* | P = .032 | ||||
| CD16−/− | No | 71 ± 17 | 75 ± 14 | 64 ± 9 | 123 ± 16 |
| Yes | 67 ± 7 | 71 ± 14 | 67 ± 15 | 129 ± 7 |
| Source of Progenitor B Cells . | 2.4G2 Added . | % HSAlo . | MFI . | %IgM+ . | MFI . |
|---|---|---|---|---|---|
| wt+/+ | No | 75 ± 13 | 77 ± 9 | 58 ± 6 | 127 ± 4 |
| Yes | 73 ± 17 | 81 ± 10 | 76 ± 7 | 140 ± 7 | |
| P = .014* | P = .032 | ||||
| CD16−/− | No | 71 ± 17 | 75 ± 14 | 64 ± 9 | 123 ± 16 |
| Yes | 67 ± 7 | 71 ± 14 | 67 ± 15 | 129 ± 7 |
Abbreviation: MFI, mean fluorescence intensity.
P values were calculated by comparison between medium with or without 2.4G2.