Probability of Survival in Ph+ ALL According to Presenting Features and Response
| Presenting Features and Response Parameters . | n . | pSUR at 4 yr . | SE . | P (Kaplan Meier test) . |
|---|---|---|---|---|
| WBC (×109/L)4-150 | ||||
| <25 | 20 | 0.59 | 0.11 | .05 (<25 v >100) |
| 25-100 | 15 | 0.67 | 0.12 | .65 (<25 v 25-100) |
| ≥100 | 26 | 0.31 | 0.09 | .02 (25-100 v >100) |
| Age (yr) | ||||
| 1-9 | 43 | 0.51 | 0.08 | .65 |
| ≥10 | 18 | 0.44 | 0.12 | |
| Male | 40 | 0.47 | 0.08 | .7 |
| Female | 21 | 0.52 | 0.11 | |
| m-BCR | 30 | 0.53 | 0.09 | .18 |
| M-BCR | 10 | 0.30 | 0.14 | |
| My marker positive | 15 | 0.27 | 0.11 | .054 |
| My marker neg. | 37 | 0.54 | 0.08 | |
| Remission after induction | 46 | 0.60 | 0.07 | .0001 |
| No remission after induction | 15 | 0.13 | 0.09 | |
| PGR | 37 | 0.73 | 0.07 | .0001 |
| PPR | 20 | 0.10 | 0.07 |
| Presenting Features and Response Parameters . | n . | pSUR at 4 yr . | SE . | P (Kaplan Meier test) . |
|---|---|---|---|---|
| WBC (×109/L)4-150 | ||||
| <25 | 20 | 0.59 | 0.11 | .05 (<25 v >100) |
| 25-100 | 15 | 0.67 | 0.12 | .65 (<25 v 25-100) |
| ≥100 | 26 | 0.31 | 0.09 | .02 (25-100 v >100) |
| Age (yr) | ||||
| 1-9 | 43 | 0.51 | 0.08 | .65 |
| ≥10 | 18 | 0.44 | 0.12 | |
| Male | 40 | 0.47 | 0.08 | .7 |
| Female | 21 | 0.52 | 0.11 | |
| m-BCR | 30 | 0.53 | 0.09 | .18 |
| M-BCR | 10 | 0.30 | 0.14 | |
| My marker positive | 15 | 0.27 | 0.11 | .054 |
| My marker neg. | 37 | 0.54 | 0.08 | |
| Remission after induction | 46 | 0.60 | 0.07 | .0001 |
| No remission after induction | 15 | 0.13 | 0.09 | |
| PGR | 37 | 0.73 | 0.07 | .0001 |
| PPR | 20 | 0.10 | 0.07 |
Abbreviation: SE, standard error.
pEFS at 4 years for WBC less than 25 × 109/L (n = 20) is 0.49 (SE, 0.11) and for WBC ≥25 × 109/L (n = 41) pEFS is 0.32 (SE, 0.08; P = .21; Kaplan Meier test).