MFI Values of Bcl-2 and Bax Expression and Bcl-2/Bax Ratio
| . | BCL-2 . | BAX . | BCL-2/BAX Ratio . | |||
|---|---|---|---|---|---|---|
| Mean MFI* . | SD +/− . | Mean MFI* . | SD +/− . | Mean Ratio† . | SD +/− . | |
| U-266-1970 | ||||||
| Exp. | 34 | 2.0 | 15 | 1.7 | 2.3 | 0.14 |
| IFN-γ | 41 | 2.1 | 16 | 2.0 | 2.3 | 0.09 |
| IFN-α | 57 | 2.1 | 24 | 1.9 | 2.3 | 0.15 |
| U-266-1984 | ||||||
| Exp. | 28 | 0.8 | 10 | 2.3 | 2.7 | 0.67 |
| IFN-γ | 33 | 7.1 | 9 | 2.1 | 3.6 | 0.05 |
| IFN-α | 50 | 3.7 | 17 | 3.5 | 3.0 | 0.39 |
| U-1958 | ||||||
| Exp. | 15 | 2.1 | 17 | 0.8 | 0.8 | 0.18 |
| IFN-γ | 14 | 1.7 | 14 | 0.3 | 1.0 | 0.14 |
| IFN-α | 15 | 0.9 | 16 | 5.6 | 1.0 | 0.30 |
| . | BCL-2 . | BAX . | BCL-2/BAX Ratio . | |||
|---|---|---|---|---|---|---|
| Mean MFI* . | SD +/− . | Mean MFI* . | SD +/− . | Mean Ratio† . | SD +/− . | |
| U-266-1970 | ||||||
| Exp. | 34 | 2.0 | 15 | 1.7 | 2.3 | 0.14 |
| IFN-γ | 41 | 2.1 | 16 | 2.0 | 2.3 | 0.09 |
| IFN-α | 57 | 2.1 | 24 | 1.9 | 2.3 | 0.15 |
| U-266-1984 | ||||||
| Exp. | 28 | 0.8 | 10 | 2.3 | 2.7 | 0.67 |
| IFN-γ | 33 | 7.1 | 9 | 2.1 | 3.6 | 0.05 |
| IFN-α | 50 | 3.7 | 17 | 3.5 | 3.0 | 0.39 |
| U-1958 | ||||||
| Exp. | 15 | 2.1 | 17 | 0.8 | 0.8 | 0.18 |
| IFN-γ | 14 | 1.7 | 14 | 0.3 | 1.0 | 0.14 |
| IFN-α | 15 | 0.9 | 16 | 5.6 | 1.0 | 0.30 |
Cells were harvested and analyzed by flow cytometry after 96 hours of incubation in the presence of IL-6 and with or without the addition of IFN-γ (1,000 U/mL) or IFN-α (1,000 U/mL).