Growth Inhibition of Mycobacterium AviumComplex in Human Macrophages Treated With Sargramostim or TNF108
| Cytokine (dose) . | Percentage of Inhibition3-150 . |
|---|---|
| rHuGM-CSF (1 U/mL) | 36 ± 6 |
| rHuGM-CSF (10 U/mL) | 58 ± 4 |
| rHuGM-CSF (100 U/mL) | 50 ± 4 |
| TNFα (50 U/mL) | 37 ± 6 |
| TNFα (500 U/mL) | 51 ± 6 |
| TNFα (5000 U/mL) | 44 ± 4 |
| rHuGM-CSF (10 U/mL) + TNFα (500 U/mL) | 41 ± 8 |
| Cytokine (dose) . | Percentage of Inhibition3-150 . |
|---|---|
| rHuGM-CSF (1 U/mL) | 36 ± 6 |
| rHuGM-CSF (10 U/mL) | 58 ± 4 |
| rHuGM-CSF (100 U/mL) | 50 ± 4 |
| TNFα (50 U/mL) | 37 ± 6 |
| TNFα (500 U/mL) | 51 ± 6 |
| TNFα (5000 U/mL) | 44 ± 4 |
| rHuGM-CSF (10 U/mL) + TNFα (500 U/mL) | 41 ± 8 |
Percentage of inhibition = (CFU in control well − CFU in well with each cytokine)/CFU in control well × 100. Values are means ± SEM.