Table 1.

The BEACOPP Scheme

BEACOPP Baseline
Dose (mg/m2) Days Route
Cyclophosphamide  650 1  IV  
Vincristine  1.4* 1  IV  
Etoposide 100  1-3   IV  
Procarbazine  100  1-7   PO 
Prednisone  40  1-14  PO  
Adriamycin  25  1 IV  
Bleomycin  10  8  IV 
BEACOPP Baseline
Dose (mg/m2) Days Route
Cyclophosphamide  650 1  IV  
Vincristine  1.4* 1  IV  
Etoposide 100  1-3   IV  
Procarbazine  100  1-7   PO 
Prednisone  40  1-14  PO  
Adriamycin  25  1 IV  
Bleomycin  10  8  IV 
BEACOPP Escalated
Level 1  Level 2  Level 3  Level 4 Level 5  Level 6  
Adriamycin  35  35  35 35  35  35  
Cyclophosphamide  800  950  1100 1250  1400  1550  
Etoposide  125  150  175 200  225  250 
BEACOPP Escalated
Level 1  Level 2  Level 3  Level 4 Level 5  Level 6  
Adriamycin  35  35  35 35  35  35  
Cyclophosphamide  800  950  1100 1250  1400  1550  
Etoposide  125  150  175 200  225  250 

G-CSF from day 8.

Abbreviations: IV, intravenously; PO, by mouth.

*

Maximal dose, 2 mg.

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