Table 3. Acute Toxicities Related to... | American Society of Hematology

Table 3.

Acute Toxicities Related to Dose Level

	Indended Dose Level
	1-3	4-6
Leukocytopenia^*	71^3-151	76
Thrombocytopenia^*	29	48
Anemia^*	21	21
Infection	3	<1
Nausea	5	2
Pain	3	4
No. of cycles/no. of patients	200/26	252/34

	Indended Dose Level
	1-3	4-6
Leukocytopenia^*	71^3-151	76
Thrombocytopenia^*	29	48
Anemia^*	21	21
Infection	3	<1
Nausea	5	2
Pain	3	4
No. of cycles/no. of patients	200/26	252/34

^*Toxicities WHO

Grade III

Grade IV

Hemoglobin

<7.9

<6.5

g/dL

Leukocytes

<1.9

<1.0

× 1,000/μL

Granulocytes

<0.9

<0.5

× 1,000/μL

Thrombocytes

<49

<25

× 1,000/μL

Percentage of cycles with WHO grade III or IV toxicities.