Frequency of Human CRU in Secondary Recipients of Marrow from Control and Growth Factor–Injected Primary Mice
| Growth Factors Injected into Primary Mice . | CRU Frequency (per 108 Murine Marrow Cells) . |
|---|---|
| Control | 1 (0.6 to 1.6) |
| SF, IL-3, GM-CSF, Ep | 10 (7 to 14) |
| FL, SF, IL-6 | 3 (2 to 4) |
| Growth Factors Injected into Primary Mice . | CRU Frequency (per 108 Murine Marrow Cells) . |
|---|---|
| Control | 1 (0.6 to 1.6) |
| SF, IL-3, GM-CSF, Ep | 10 (7 to 14) |
| FL, SF, IL-6 | 3 (2 to 4) |
Values shown are for CRU with the range defined by ± SE shown in parentheses. SF, IL-3, GM-CSF, and Ep at 10 μg, 6 μg, 6 μg, and 10 U per injection, respectively, 3 × week for 2 weeks before sacrifice. FL, SF, and IL-6 daily at 1 μg, 1 μg, and 0.25 μg per injection, respectively, for 1 month before sacrifice or 10 μg, 10 μg, and 2 μg per injection, respectively, 3 × week for 2 weeks before sacrifice.