Table 1. Downregulation and Upregulation... | American Society of Hematology

Table 1.

Downregulation and Upregulation of the c-kit mRNA Levels Are Immediate Consequences of Stroma Cell Interaction

Clones	Relative Level of c-kit mRNA Expression
Clones	Continuous Growth on	Removal of	Reexposure to Stroma
TF-1S #MB6	1 ± 0.2^*	7,980 ± 1,860^*	9 ± 2^*
TF-1S #MB8	1 ± 0.3^†	360 ± 100^†	4 ± 1^†

Clones	Relative Level of c-kit mRNA Expression
Clones	Continuous Growth on	Removal of	Reexposure to Stroma
TF-1S #MB6	1 ± 0.2^*	7,980 ± 1,860^*	9 ± 2^*
TF-1S #MB8	1 ± 0.3^†	360 ± 100^†	4 ± 1^†

The mRNA levels of the TF-1S clones each were set to 1. The c-kit mRNA level of #MB8 is 2.7-fold higher than the c-kit mRNA level of #MB6. Removal of and reexposure to stroma was performed for a period of 2 days each.

n = 4.

†

n = 3.

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