Antitumor Effects of As2O3 and Ascorbic Acid Alone or in Combination in Mice Bearing P388D1 Lymphoma
| Treatment . | Weight Change (g) . | Survival Time (d) . | ILS (%) . |
|---|---|---|---|
| Control | 1.7 | 23.7 ± 1.3 | 0 |
| As2O3 | 4.9 | 22.8 ± 2.0 | −3.8 |
| AA | 2.5 | 25.0 ± 4.3 | 5.4 |
| As2O3 + AA | 1.6 | 33.2 ± 8.25-150 | 40.1 |
| Treatment . | Weight Change (g) . | Survival Time (d) . | ILS (%) . |
|---|---|---|---|
| Control | 1.7 | 23.7 ± 1.3 | 0 |
| As2O3 | 4.9 | 22.8 ± 2.0 | −3.8 |
| AA | 2.5 | 25.0 ± 4.3 | 5.4 |
| As2O3 + AA | 1.6 | 33.2 ± 8.25-150 | 40.1 |
As2O3 5 mg/kg or AA 500 mg/kg was given intraperitoneally every other day for 7 times. Weight was measured before any treatment and after the last treatment.
Abbreviation: ILS, increase in lifespan over control.
P < .05.