Table 1.

Estimated Radiation Absorbed Doses (Gy/mCi131I) for 30F11 Antibody and Rat IgG

Tissue30F11 (Gy/mCi) Rat IgG (Gy/mCi)
Spleen  107.7 23.7  
Marrow  34.8  25.4  
Axillary lymph node  65.5 21.7  
Brachial lymph node  70.3  24.3  
Thymus  12.8 33.3  
Lung  16.7  44.8  
Liver  10.7  19.9 
Kidney  12.5  24.5  
Stomach  10.4  15.2  
Total body  5.9  18.7 
Tissue30F11 (Gy/mCi) Rat IgG (Gy/mCi)
Spleen  107.7 23.7  
Marrow  34.8  25.4  
Axillary lymph node  65.5 21.7  
Brachial lymph node  70.3  24.3  
Thymus  12.8 33.3  
Lung  16.7  44.8  
Liver  10.7  19.9 
Kidney  12.5  24.5  
Stomach  10.4  15.2  
Total body  5.9  18.7 

Estimates of radiation absorbed doses calculated from time-activity curves of trace-iodinated 30F11 antibody and rat IgG from experiment shown in Fig 1, assuming that each was labeled with131I. Radiation doses are expressed as grays delivered per millicurie of 131I administered.

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