Engraftment of Congenic Marrow in Mice After131I-Anti-CD45 Antibody
| Administered 131I Activity . | % Donor Granulocytes (mean ± SD) . | % Donor T Cells (mean ± SD) . | ||
|---|---|---|---|---|
| 28 d After BMT . | 113 d After BMT . | 28 d After BMT . | 113 d After BMT . | |
| 0 (Ab only) | 4.9 ± 5.6 | 1.6 ± 0.9 | 0 ± 0 | 0.1 ± .2 |
| 0.5 mCi | 81.3 ± 7.5 | 86.6 ± 7.0 | 34.7 ± 8.1 | 80.4 ± 7.6 |
| 1.0 mCi | 92.7 ± 3.5 | 91.5 ± 3.7 | 38.5 ± 9.4 | 87.6 ± 3.5 |
| 1.25 mCi | 96.0 ± 2.9 | 95.8 ± 3.2 | 44.9 ± 9.8 | 89.1 ± 4.9 |
| 1.5 mCi | 98.3 ± 1.4 | 94.9 ± 7.7 | 38.1 ± 14.8 | 89.8 ± 4.3 |
| Administered 131I Activity . | % Donor Granulocytes (mean ± SD) . | % Donor T Cells (mean ± SD) . | ||
|---|---|---|---|---|
| 28 d After BMT . | 113 d After BMT . | 28 d After BMT . | 113 d After BMT . | |
| 0 (Ab only) | 4.9 ± 5.6 | 1.6 ± 0.9 | 0 ± 0 | 0.1 ± .2 |
| 0.5 mCi | 81.3 ± 7.5 | 86.6 ± 7.0 | 34.7 ± 8.1 | 80.4 ± 7.6 |
| 1.0 mCi | 92.7 ± 3.5 | 91.5 ± 3.7 | 38.5 ± 9.4 | 87.6 ± 3.5 |
| 1.25 mCi | 96.0 ± 2.9 | 95.8 ± 3.2 | 44.9 ± 9.8 | 89.1 ± 4.9 |
| 1.5 mCi | 98.3 ± 1.4 | 94.9 ± 7.7 | 38.1 ± 14.8 | 89.8 ± 4.3 |
Engraftment of T-cell–depleted C57BL/6 marrow in B6-Ly5a recipients. Values are the mean for 3 (antibody only) to 5 or 6 mice per group.