Table 1.

Relation of Presenting Cellular Features With Leukemic Cell Recovery After Culture on Stroma

Feature Category Percent Cell Recovery*P Value
≤91% >91%
Lineage  T  7  8  .791  
 B  57  57 
Differentiation  Early B  41  32  .175  
 Pre B 17  23  
Adverse genetic features Yes  8  17 .047  
 No  56  46  
TEL rearrangements Yes  12  19  .206  
 No  42  37 
Hyperdiploidy 51-to-65  Yes  23  2  <.001  
 No 41  63 
Feature Category Percent Cell Recovery*P Value
≤91% >91%
Lineage  T  7  8  .791  
 B  57  57 
Differentiation  Early B  41  32  .175  
 Pre B 17  23  
Adverse genetic features Yes  8  17 .047  
 No  56  46  
TEL rearrangements Yes  12  19  .206  
 No  42  37 
Hyperdiploidy 51-to-65  Yes  23  2  <.001  
 No 41  63 
*

The median percentage of leukemic cells recovered after 7 days of culture on stromal layers relative to the number of cells originally seeded was 91% (range, <1% to 550%).

By Fisher’s exact test.

Cases with t(9;22), t(1;19) or MLL gene rearrangements.

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