HCA Expression in Stromal Compartments of Human Hematopoietic Tissues
| Organ/Tissue . | Expression . | Cell Type/Localization . |
|---|---|---|
| Yolk sac | + | Endoderm |
| Paraaortic embryonic mesoderm | + | Ventrolateral mesenchyme* |
| Embryonic liver | + | Hepatocytes |
| Fetal liver | + | Hepatocytes, Kupffer cells |
| Fetal thymus | + | Subcapsular epithelium, subsets of cortical and medullary epithelial cells, Hassall’s bodies |
| Fetal bone marrow | + | Vascular pericytes, osteoblasts* |
| Adult bone marrow | + | Adherent cells in primary cultures Myofibroblasts in vitro |
| Fetal spleen | − | |
| Fetal lymph nodes | − |
| Organ/Tissue . | Expression . | Cell Type/Localization . |
|---|---|---|
| Yolk sac | + | Endoderm |
| Paraaortic embryonic mesoderm | + | Ventrolateral mesenchyme* |
| Embryonic liver | + | Hepatocytes |
| Fetal liver | + | Hepatocytes, Kupffer cells |
| Fetal thymus | + | Subcapsular epithelium, subsets of cortical and medullary epithelial cells, Hassall’s bodies |
| Fetal bone marrow | + | Vascular pericytes, osteoblasts* |
| Adult bone marrow | + | Adherent cells in primary cultures Myofibroblasts in vitro |
| Fetal spleen | − | |
| Fetal lymph nodes | − |
As determined by in situ hybridization.