Correlation of Patient and Disease Characteristics in Early Chronic Phase With Methylation Profile (N = 82)
| Characteristic . | Category . | No. . | No. (%) With High Methylation . | P Value . |
|---|---|---|---|---|
| Age (yr) | <50 | 59 | 28 (47) | |
| >50 | 23 | 9 (39) | .5 | |
| Gender | Male | 60 | 27 (45) | |
| Female | 22 | 10 (45) | .97 | |
| Hemoglobin (g/dL) | <10 | 14 | 7 (50) | |
| >10 | 68 | 30 (44) | .69 | |
| Platelets (×109/L) | <450 | 50 | 20 (40) | |
| >450 | 31 | 16 (52) | .31 | |
| Splenomegaly | Yes | 36 | 18 (50) | |
| No | 44 | 19 (43) | .54 | |
| WBC (×109/L) | <50 | 27 | 6 (22) | |
| >50 | 55 | 31 (56) | .004 | |
| Risk group | Good | 38 | 13 (34) | |
| Intermediate | 24 | 14 (58) | .16 | |
| Poor | 10 | 5 (50) |
| Characteristic . | Category . | No. . | No. (%) With High Methylation . | P Value . |
|---|---|---|---|---|
| Age (yr) | <50 | 59 | 28 (47) | |
| >50 | 23 | 9 (39) | .5 | |
| Gender | Male | 60 | 27 (45) | |
| Female | 22 | 10 (45) | .97 | |
| Hemoglobin (g/dL) | <10 | 14 | 7 (50) | |
| >10 | 68 | 30 (44) | .69 | |
| Platelets (×109/L) | <450 | 50 | 20 (40) | |
| >450 | 31 | 16 (52) | .31 | |
| Splenomegaly | Yes | 36 | 18 (50) | |
| No | 44 | 19 (43) | .54 | |
| WBC (×109/L) | <50 | 27 | 6 (22) | |
| >50 | 55 | 31 (56) | .004 | |
| Risk group | Good | 38 | 13 (34) | |
| Intermediate | 24 | 14 (58) | .16 | |
| Poor | 10 | 5 (50) |