Individual B and Plasma Cells in MM But Not in Normal Donors Express RHAMM Transcripts as Measured by In Situ RT-PCR With Primers Annealing to RHAMM
. | % Indicated Subset Expressing RHAMM Transcripts3-150 . | ||
---|---|---|---|
MM Plasma Cells . | MM B Cells . | Normal B Cells . | |
35.3 | 12.6 | 1.8 | |
22.7 | 13.4 | 1.1 | |
29.1 | 10.9 | <1 | |
26.5 | 15.1 | 1.7 | |
22.3 | 8.0 | ||
35.9 | 11.7 | ||
Mean ± SE | 28.6 ± 2.43-151 | 11.8 ± 13-152 | 1.1 ± 0.4 |
. | % Indicated Subset Expressing RHAMM Transcripts3-150 . | ||
---|---|---|---|
MM Plasma Cells . | MM B Cells . | Normal B Cells . | |
35.3 | 12.6 | 1.8 | |
22.7 | 13.4 | 1.1 | |
29.1 | 10.9 | <1 | |
26.5 | 15.1 | 1.7 | |
22.3 | 8.0 | ||
35.9 | 11.7 | ||
Mean ± SE | 28.6 ± 2.43-151 | 11.8 ± 13-152 | 1.1 ± 0.4 |
Each data point represents the indicated type of sorted cells from an individual MM or normal donor, as described in Materials and Methods. MM plasma cells were from BM, and MM B cells and normal B cells were from blood.
P < .001 as compared with MM B cells.
P < .001 as compared with B cells from normal donors.