Hematology and RBC Cation Content of 7.2b Knock-Out Mice
| . | 7.2b-Deficient Mice . | Control Mice . |
|---|---|---|
| Parameter | (Δ7.2b/Δ7.2b) | (+//+) |
| RBC cations | ||
| Na+(mmol/L RBC) | 5.1 ± 0.8 | 4.6 ± 0.6 |
| K+(mmol/L RBC) | 133.4 ± 4.0 | 132.3 ± 4.6 |
| Na+ + K+ (mmol/L RBC) | 138.5 ± 4.5 | 136.9 ± 4.6 |
| Hematology | ||
| Hematocrit (%) | 52.8 ± 1.0 | 51.4 ± 1.8 |
| Reticulocytes (%) | 2.4 ± 0.7 | 2.4 ± 0.7 |
| MCV (fL) | 43.0 ± 1.2 | 43.5 ± 0.9 |
| MCHC (g/dL) | 30.0 ± 0.8 | 30.3 ± 0.7 |
| . | 7.2b-Deficient Mice . | Control Mice . |
|---|---|---|
| Parameter | (Δ7.2b/Δ7.2b) | (+//+) |
| RBC cations | ||
| Na+(mmol/L RBC) | 5.1 ± 0.8 | 4.6 ± 0.6 |
| K+(mmol/L RBC) | 133.4 ± 4.0 | 132.3 ± 4.6 |
| Na+ + K+ (mmol/L RBC) | 138.5 ± 4.5 | 136.9 ± 4.6 |
| Hematology | ||
| Hematocrit (%) | 52.8 ± 1.0 | 51.4 ± 1.8 |
| Reticulocytes (%) | 2.4 ± 0.7 | 2.4 ± 0.7 |
| MCV (fL) | 43.0 ± 1.2 | 43.5 ± 0.9 |
| MCHC (g/dL) | 30.0 ± 0.8 | 30.3 ± 0.7 |
RBC cation determinations were performed on control (n = 4) and 7.2-deficient (n = 5) mice. Hematologic measurements were performed on control (n = 8) and 7.2b-deficient (n = 8) mice. Values shown are mean ± standard deviation. The 7.2b-deficient and control mice did not differ in any of the measured parameters (analyzed byt-test).