Peripheral Blood Counts After Filgrastim Priming and Cladribine Therapy
| . | Filgrastim + Cladribine . | Cladribine Alone . | PValue . |
|---|---|---|---|
| Peak counts after filgrastim priming (day 0) | |||
| WBC (×109/L) | |||
| Median (range) | 3.9 (1.6-64.5) | ||
| ANC (×109/L) | |||
| Median (range) | 2.26 (0.18-29.03) | ||
| Hemoglobin (g/dL) | |||
| Median (range) | 12.4 (6.8-15.7) | ||
| Platelets (×109/L) | |||
| Median (range) | 82 (23-162) | ||
| Absolute hairy cell count (×106/L) | |||
| Median (range) | 80 (0-32,250) | ||
| Nadir counts after cladribine | |||
| WBC (×109/L) | |||
| Median (range) | 0.8 (0-1.8) | 0.6 (0-7.1) | .15 |
| ANC (×109/L) | |||
| Median (range) | 0.53 (0-1.8) | 0.29 (0-1.96) | .04* |
| Hemoglobin (g/dL) | |||
| Median (range) | 10.2 (3.7-15.2) | 9.2 (4.8-14.3) | .12 |
| Platelets (×109/L) | |||
| Median (range) | 64 (16-130) | 68 (3-359) | .33 |
| . | Filgrastim + Cladribine . | Cladribine Alone . | PValue . |
|---|---|---|---|
| Peak counts after filgrastim priming (day 0) | |||
| WBC (×109/L) | |||
| Median (range) | 3.9 (1.6-64.5) | ||
| ANC (×109/L) | |||
| Median (range) | 2.26 (0.18-29.03) | ||
| Hemoglobin (g/dL) | |||
| Median (range) | 12.4 (6.8-15.7) | ||
| Platelets (×109/L) | |||
| Median (range) | 82 (23-162) | ||
| Absolute hairy cell count (×106/L) | |||
| Median (range) | 80 (0-32,250) | ||
| Nadir counts after cladribine | |||
| WBC (×109/L) | |||
| Median (range) | 0.8 (0-1.8) | 0.6 (0-7.1) | .15 |
| ANC (×109/L) | |||
| Median (range) | 0.53 (0-1.8) | 0.29 (0-1.96) | .04* |
| Hemoglobin (g/dL) | |||
| Median (range) | 10.2 (3.7-15.2) | 9.2 (4.8-14.3) | .12 |
| Platelets (×109/L) | |||
| Median (range) | 64 (16-130) | 68 (3-359) | .33 |
Nominally significant at α level .05 (P < .05).