Table 2.

Odds Ratios as Estimates of Relative Risk for MI in GPIa-IIa T807 Allele Carriers

n − MI+ MI Odds Ratio (95% CI) 2P
n (−T) n (+T) n (−T) n (+T)
Total sample  2,237  416  771  334  716  1.13 (0.91-1.40) .25  
Age <62 yrs* 1,057  226  350  152  329 1.57 (1.14-2.13)  .004  
Age <49 yrs† 223  56 76  27  64  2.61 (1.26-5.41)  .009  
Age <62 yrs* 503  112  159  73  159  1.94 (1.25-3.01)  .003 
BMI >26.9 kg/m2 * 
Age <49 yrs† 117  26 39  12  40  4.92 (1.71-14.2)  .003  
BMI >26.9 kg/m2 * 
n − MI+ MI Odds Ratio (95% CI) 2P
n (−T) n (+T) n (−T) n (+T)
Total sample  2,237  416  771  334  716  1.13 (0.91-1.40) .25  
Age <62 yrs* 1,057  226  350  152  329 1.57 (1.14-2.13)  .004  
Age <49 yrs† 223  56 76  27  64  2.61 (1.26-5.41)  .009  
Age <62 yrs* 503  112  159  73  159  1.94 (1.25-3.01)  .003 
BMI >26.9 kg/m2 * 
Age <49 yrs† 117  26 39  12  40  4.92 (1.71-14.2)  .003  
BMI >26.9 kg/m2 * 

The presence of the T allele in CT heterozygotes and TT homozygotes was compared between individuals with and without MI. Odds ratios were calculated as an estimate of relative risk of MI associated with the T allele and adjusted to risk factors of MI; for these odds ratios, we calculated two-tailed P values by multiple logistic regression with adjustment for additional risk factors of MI.

*

Mean age or mean BMI.

†

10th percentile of age.

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