Characteristics of the 247 Patients With FL According to the Site of the Bcl-2 Rearrangement
. | Percent of Patients . | ||
---|---|---|---|
mcr (n = 27) . | MBR (n = 175) . | G-MBR/mcr (n = 45) . | |
Male gender (%) | 44 | 48 | 55 |
Age ≥60 yr (%) | 30 | 30 | 41 |
Histologic subtype (%) | |||
Grade I | 67 | 63 | 60 |
Grade II | 30 | 34 | 36 |
Grade III | 4 | 3 | 4 |
Bulky disease (%) | 23 | 22 | 16 |
Ann Arbor stage (%) | |||
I-II | 33 | 20 | 11 |
III | 11 | 17 | 27 |
IV | 56 | 63 | 62 |
Extranodal involvement ≥1 site (%) | 67 | 69 | 66 |
Bone marrow (+) (%) | 52 | 57 | 53 |
Serum LDH level (median) | 431 | 472 | 491 |
Serum β2M level (median) | 1.7 | 1.9 | 2.2 |
. | Percent of Patients . | ||
---|---|---|---|
mcr (n = 27) . | MBR (n = 175) . | G-MBR/mcr (n = 45) . | |
Male gender (%) | 44 | 48 | 55 |
Age ≥60 yr (%) | 30 | 30 | 41 |
Histologic subtype (%) | |||
Grade I | 67 | 63 | 60 |
Grade II | 30 | 34 | 36 |
Grade III | 4 | 3 | 4 |
Bulky disease (%) | 23 | 22 | 16 |
Ann Arbor stage (%) | |||
I-II | 33 | 20 | 11 |
III | 11 | 17 | 27 |
IV | 56 | 63 | 62 |
Extranodal involvement ≥1 site (%) | 67 | 69 | 66 |
Bone marrow (+) (%) | 52 | 57 | 53 |
Serum LDH level (median) | 431 | 472 | 491 |
Serum β2M level (median) | 1.7 | 1.9 | 2.2 |
Abbreviation: G-MBR/mcr, germline for MBRand mcr.