Table 1.

Colt Screen for HPK1 Binding SH3-Domain Containing Proteins

HIP 21 Drebrin  
HIP 25  Drebrin  
HIP 51* Ray  
HIP 53 Drebrin  
HIP 54* Ray  
HIP 62  Lasp1  
HIP 64 Drebrin  
HIP 65 Drebrin  
HIP 67  Drebrin  
HIP 68 Cortactin  
HIP 71  Drebrin  
HIP 74  HS1 
HIP 21 Drebrin  
HIP 25  Drebrin  
HIP 51* Ray  
HIP 53 Drebrin  
HIP 54* Ray  
HIP 62  Lasp1  
HIP 64 Drebrin  
HIP 65 Drebrin  
HIP 67  Drebrin  
HIP 68 Cortactin  
HIP 71  Drebrin  
HIP 74  HS1 

A biotinylated peptide comprising the second proline-rich motif of HPK1 was used to screen a day-14 mouse λ cDNA embryonic library. Twelve cDNAs of potential HPK1-interacting proteins (HIPs) were isolated and sequenced; entities that were derived from identical parental phages are indicated by

*

and

. A DNA database search identified all isolated sequences.

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